日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Transcription Factor 21 Regulates Cardiac Myofibroblast Formation and Fibrosis

转录因子21调控心肌成纤维细胞的形成和纤维化

Johansen, Anne Katrine Z; Kasam, Rajesh K; Vagnozzi, Ronald J; Lin, Suh-Chin J; Gomez-Arroyo, Jose; Shittu, Adenike; Bowers, Stephanie L K; Kuwabara, Yasuhide; Grimes, Kelly M; Warrick, Kathrynne; Sargent, Michelle A; Baldwin, Tanya A; Quaggin, Susan E; Barski, Artem; Molkentin, Jeffery D

A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy

人类FLII基因变异会改变肌节肌动蛋白细丝的长度,并易导致心肌病。

Kuwabara, Yasuhide; York, Allen J; Lin, Suh-Chin; Sargent, Michelle A; Grimes, Kelly M; Pirruccello, James P; Molkentin, Jeffery D

MCUb Induction Protects the Heart From Postischemic Remodeling

MCUb诱导可保护心脏免受缺血后重塑的影响

Huo, Jiuzhou; Lu, Shan; Kwong, Jennifer Q; Bround, Michael J; Grimes, Kelly M; Sargent, Michelle A; Brown, Milton E; Davis, Michael E; Bers, Donald M; Molkentin, Jeffery D

Fibroblast-Specific Genetic Manipulation of p38 Mitogen-Activated Protein Kinase In Vivo Reveals Its Central Regulatory Role in Fibrosis.

体内成纤维细胞特异性基因操作 p38 丝裂原活化蛋白激酶揭示其在纤维化中的核心调控作用

Molkentin Jeffery D, Bugg Darrian, Ghearing Natasha, Dorn Lisa E, Kim Peter, Sargent Michelle A, Gunaje Jagadambika, Otsu Kinya, Davis Jennifer

Mitsugumin 29 regulates t-tubule architecture in the failing heart

Mitsugumin 29 调节衰竭心脏中的横管结构

Correll, Robert N; Lynch, Jeffrey M; Schips, Tobias G; Prasad, Vikram; York, Allen J; Sargent, Michelle A; Brochet, Didier X P; Ma, Jianjie; Molkentin, Jeffery D

Genetic Analysis of Connective Tissue Growth Factor as an Effector of Transforming Growth Factor β Signaling and Cardiac Remodeling

结缔组织生长因子作为转化生长因子β信号传导和心脏重塑效应因子的遗传分析

Accornero, Federica; van Berlo, Jop H; Correll, Robert N; Elrod, John W; Sargent, Michelle A; York, Allen; Rabinowitz, Joseph E; Leask, Andrew; Molkentin, Jeffery D

Enhanced Ca²⁺ influx from STIM1-Orai1 induces muscle pathology in mouse models of muscular dystrophy

STIM1-Orai1介导的Ca²⁺内流增强可诱导小鼠肌营养不良模型出现肌肉病理改变

Goonasekera, Sanjeewa A; Davis, Jennifer; Kwong, Jennifer Q; Accornero, Federica; Wei-LaPierre, Lan; Sargent, Michelle A; Dirksen, Robert T; Molkentin, Jeffery D

P38α MAPK underlies muscular dystrophy and myofiber death through a Bax-dependent mechanism

P38α MAPK 通过 Bax 依赖性机制导致肌营养不良和肌纤维死亡。

Wissing, Erin R; Boyer, Justin G; Kwong, Jennifer Q; Sargent, Michelle A; Karch, Jason; McNally, Elizabeth M; Otsu, Kinya; Molkentin, Jeffery D

Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice

Bax和Bak作为线粒体通透性孔的外膜成分,在小鼠中调控坏死性细胞死亡。

Karch, Jason; Kwong, Jennifer Q; Burr, Adam R; Sargent, Michelle A; Elrod, John W; Peixoto, Pablo M; Martinez-Caballero, Sonia; Osinska, Hanna; Cheng, Emily H-Y; Robbins, Jeffrey; Kinnally, Kathleen W; Molkentin, Jeffery D

Calcineurin protects the heart in a murine model of dilated cardiomyopathy

钙调磷酸酶在扩张型心肌病小鼠模型中具有心脏保护作用。

Heineke, Joerg; Wollert, Kai C; Osinska, Hanna; Sargent, Michelle A; York, Allen J; Robbins, Jeffrey; Molkentin, Jeffery D