PARP1 regulates the genomic ribonucleotide processing activity of TOP1 to prevent the formation of toxic TOP1-DNA adducts and the associated mutations
PARP1 调节 TOP1 的基因组核糖核苷酸加工活性,以防止形成有毒的 TOP1-DNA 加合物及其相关突变。
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doi:10.64898/2026.02.05.703798
Kesimoglu, Ziynet Nesibe; Hodzic, Ermin; Hoinka, Jan; Amgalan, Bayarbaatar; Hirsch, M G; Przytycka, Teresa M; Sarrain, Edward James; Wang, Quan; Bondoy, Angel Caitlin; Guo, Feng; Cao, Qi; Niu, Hengyao