日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A phase 1 trial of fully human BCMA CAR-T therapy for relapsed/refractory multiple myeloma with 5-year follow-up

一项针对复发/难治性多发性骨髓瘤的全人源BCMA CAR-T疗法的I期临床试验,随访时间为5年。

Tuazon, Sherilyn A; Portuguese, Andrew J; Pont, Margot J; Cowan, Andrew J; Cole, Gabriel O; Sather, Blythe D; Song, Xiaoling; Thomas, Sushma; Wood, Brent L; Blake, Michelle; Works, Melissa G; Shadman, Mazyar; Liang, Emily C; Wu, Qian V; Voutsinas, Jenna M; Gooley, Ted A; Turtle, Cameron J; Till, Brian G; Coffey, David G; Maloney, David G; Riddell, Stanley R; Green, Damian J

γ-Secretase inhibitor in combination with BCMA chimeric antigen receptor T-cell immunotherapy for individuals with relapsed or refractory multiple myeloma: a phase 1, first-in-human trial

γ-分泌酶抑制剂联合BCMA嵌合抗原受体T细胞免疫疗法治疗复发或难治性多发性骨髓瘤患者:一项I期首次人体试验

Cowan, Andrew J; Pont, Margot J; Sather, Blythe D; Turtle, Cameron J; Till, Brian G; Libby, Edward N 3rd; Coffey, David G; Tuazon, Sherilyn A; Wood, Brent; Gooley, Ted; Wu, Vicky Q; Voutsinas, Jenna; Song, Xiaoling; Shadman, Mazyar; Gauthier, Jordan; Chapuis, Aude G; Milano, Filippo; Maloney, David G; Riddell, Stanley R; Green, Damian J

Trypanosoma cruzi trans-sialidase initiates a program independent of the transcription factors RORγt and Ahr that leads to IL-17 production by activated B cells.

克氏锥虫转唾液酸酶启动一个不依赖于转录因子 RORγt 和 Ahr 的程序,该程序导致活化的 B 细胞产生 IL-17

Bermejo Daniela A, Jackson Shaun W, Gorosito-Serran Melisa, Acosta-Rodriguez Eva V, Amezcua-Vesely Maria C, Sather Blythe D, Singh Akhilesh K, Khim Socheath, Mucci Juan, Liggitt Denny, Campetella Oscar, Oukka Mohamed, Gruppi Adriana, Rawlings David J

Ubiquitous high-level gene expression in hematopoietic lineages provides effective lentiviral gene therapy of murine Wiskott-Aldrich syndrome

造血谱系中普遍存在的高水平基因表达为小鼠Wiskott-Aldrich综合征的慢病毒基因治疗提供了有效途径。

Astrakhan, Alexander; Sather, Blythe D; Ryu, Byoung Y; Khim, Socheath; Singh, Swati; Humblet-Baron, Stephanie; Ochs, Hans D; Miao, Carol H; Rawlings, David J

WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity

WASp缺陷型B细胞在引发自身免疫中发挥着关键的细胞内在作用。

Becker-Herman, Shirly; Meyer-Bahlburg, Almut; Schwartz, Marc A; Jackson, Shaun W; Hudkins, Kelly L; Liu, Chaohong; Sather, Blythe D; Khim, Socheath; Liggitt, Denny; Song, Wenxia; Silverman, Gregg J; Alpers, Charles E; Rawlings, David J

Cellular requirements for diabetes induction in DO11.10xRIPmOVA mice

DO11.10xRIPmOVA小鼠糖尿病诱导的细胞需求

Wesley, Johnna D; Sather, Blythe D; Perdue, Nikole R; Ziegler, Steven F; Campbell, Daniel J