Design, Multigram Synthesis, and in Vitro and in Vivo Evaluation of Propylamycin: A Semisynthetic 4,5-Deoxystreptamine Class Aminoglycoside for the Treatment of Drug-Resistant Enterobacteriaceae and Other Gram-Negative Pathogens
丙吡拉霉素的设计、多克级合成、体外和体内评价：一种用于治疗耐药肠杆菌科细菌和其他革兰氏阴性病原体的半合成4,5-脱氧链霉胺类氨基糖苷
期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.9b01693
Matsushita, Takahiko; Sati, Girish C; Kondasinghe, Nuwan; Pirrone, Michael G; Kato, Takayuki; Waduge, Prabuddha; Kumar, Harshitha Santhosh; Sanchon, Adrian Cortes; Dobosz-Bartoszek, Malgorzata; Shcherbakov, Dimitri; Juhas, Mario; Hobbie, Sven N; Schrepfer, Thomas; Chow, Christine S; Polikanov, Yury S; Schacht, Jochen; Vasella, Andrea; Böttger, Erik C; Crich, David
