日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The influence of murine cytomegalovirus infection on susceptibility to mycobacterial infection

小鼠巨细胞病毒感染对分枝杆菌感染易感性的影响

Li, Shuailin; Hutchings, Claire; Korompis, Marcellus; De Voss, Christopher; Ateere, Alberta; Satti, Iman; Klenerman, Paul; McShane, Helen; Stylianou, Elena

MetE: a promising protective antigen for tuberculosis vaccine development.

MetE:一种有前景的结核病疫苗开发保护性抗原

Almujri Salem Salman, Stylianou Elena, Nicastri Annalisa, Satti Iman, Korompis Marcellus, Li Shuailin, De Voss Christopher J, Polo Peralta Alvarez Marco, Tanner Rachel, Bettencourt Paulo J G, Ternette Nicola, McShane Helen

Safety and immunogenicity of ChAdOx1 85A prime followed by MVA85A boost compared with BCG revaccination among Ugandan adolescents who received BCG at birth: a randomised, open-label trial

在出生时接种过卡介苗的乌干达青少年中,ChAdOx1 85A 初免后接种 MVA85A 加强针与卡介苗再次接种相比的安全性和免疫原性:一项随机、开放标签试验

Wajja, Anne; Nassanga, Beatrice; Natukunda, Agnes; Serubanja, Joel; Tumusiime, Josephine; Akurut, Helen; Oduru, Gloria; Nassuuna, Jacent; Kabagenyi, Joyce; Morrison, Hazel; Scott, Hannah; Doherty, Rebecca Powell; Marshall, Julia L; Puig, Ingrid Cabrera; Cose, Stephen; Kaleebu, Pontiano; Webb, Emily L; Satti, Iman; McShane, Helen; Elliott, Alison M

Safety of a controlled human infection model of tuberculosis with aerosolised, live-attenuated Mycobacterium bovis BCG versus intradermal BCG in BCG-naive adults in the UK: a dose-escalation, randomised, controlled, phase 1 trial

在英国一项剂量递增、随机、对照的1期临床试验中,比较了气溶胶吸入减毒活牛分枝杆菌卡介苗与皮内注射卡介苗在未接种过卡介苗的成年人中感染结核病的安全性:一项受控的人体感染模型研究

Satti, Iman; Marshall, Julia L; Harris, Stephanie A; Wittenberg, Rachel; Tanner, Rachel; Lopez Ramon, Raquel; Wilkie, Morven; Ramos Lopez, Fernando; Riste, Michael; Wright, Daniel; Peralta Alvarez, Marco Polo; Williams, Nicola; Morrison, Hazel; Stylianou, Elena; Folegatti, Pedro; Jenkin, Daniel; Vermaak, Samantha; Rask, Linnea; Cabrera Puig, Ingrid; Powell Doherty, Rebecca; Lawrie, Alison; Moss, Paul; Hinks, Timothy; Bettinson, Henry; McShane, Helen

Safety, tolerability, viral kinetics, and immune correlates of protection in healthy, seropositive UK adults inoculated with SARS-CoV-2: a single-centre, open-label, phase 1 controlled human infection study

在接种 SARS-CoV-2 的健康、血清阳性英国成年人中,安全性、耐受性、病毒动力学和免疫保护相关性:一项单中心、开放标签、1 期对照人体感染研究

Jackson, Susan; Marshall, Julia L; Mawer, Andrew; Lopez-Ramon, Raquel; Harris, Stephanie A; Satti, Iman; Hughes, Eileen; Preston-Jones, Hannah; Cabrera Puig, Ingrid; Longet, Stephanie; Tipton, Tom; Laidlaw, Stephen; Doherty, Rebecca Powell; Morrison, Hazel; Mitchell, Robert; Tanner, Rachel; Ateere, Alberta; Stylianou, Elena; Wu, Meng-San; Fredsgaard-Jones, Timothy P W; Breuer, Judith; Rapeport, Garth; Ferreira, Vanessa M; Gleeson, Fergus; Pollard, Andrew J; Carroll, Miles; Catchpole, Andrew; Chiu, Christopher; McShane, Helen

A dose escalation study to evaluate the safety of an aerosol BCG infection in previously BCG-vaccinated healthy human UK adults

一项剂量递增研究,旨在评估气溶胶卡介苗感染对既往接种过卡介苗的健康英国成年人的安全性。

Fredsgaard-Jones, Timothy; Harris, Stephanie A; Morrison, Hazel; Ateere, Alberta; Nassanga, Beatrice; Ramon, Raquel Lopez; Mitton, Celia; Fletcher, Eve; Decker, Jonathan; Preston-Jones, Hannah; Jackson, Susan; Mawer, Andrew; Satti, Iman; Barer, Michael; Hinks, Timothy; Bettinson, Henry; McShane, Helen

Mtb-Specific HLA-E-Restricted T Cells Are Induced during Mtb Infection but Not after BCG Administration in Non-Human Primates and Humans.

在非人灵长类动物和人类中,结核分枝杆菌感染期间会诱导产生结核分枝杆菌特异性 HLA-E 限制性 T 细胞,但在接种卡介苗后则不会

Voogd Linda, van Wolfswinkel Marjolein, Satti Iman, White Andrew D, Dijkman Karin, Gela Anele, van Meijgaarden Krista E, Franken Kees L M C, Marshall Julia L, Ottenhoff Tom H M, Scriba Thomas J, McShane Helen, Sharpe Sally A, Verreck Frank A W, Joosten Simone A

Intravenous BCG vaccination in non-human primates induces superior serum antibody titers with enhanced avidity and opsonizing capacity compared to the intradermal route

与皮内注射途径相比,非人灵长类动物静脉注射卡介苗可诱导产生更高滴度的血清抗体,且抗体具有更强的亲和力和调理能力。

Peralta Alvarez, Marco Polo; Downward, Keya; White, Andrew; Harris, Stephanie A; Satti, Iman; Li, Shuailin; Morrison, Alexandra; Sibley, Laura; Sarfas, Charlotte; Dennis, Mike; Azema, Hugo Redondo; Sharpe, Sally; McShane, Helen; Tanner, Rachel

Inflammation and immune activation are associated with risk of Mycobacterium tuberculosis infection in BCG-vaccinated infants

炎症和免疫激活与接种过卡介苗的婴儿感染结核分枝杆菌的风险相关。

Satti, Iman; Wittenberg, Rachel E; Li, Shuailin; Harris, Stephanie A; Tanner, Rachel; Cizmeci, Deniz; Jacobs, Ashley; Williams, Nicola; Mulenga, Humphrey; Fletcher, Helen A; Scriba, Thomas J; Tameris, Michele; Hatherill, Mark; McShane, Helen

Induction of Functional Specific Antibodies, IgG-Secreting Plasmablasts and Memory B Cells Following BCG Vaccination

卡介苗接种后功能性特异性抗体、IgG分泌浆细胞和记忆B细胞的诱导

Bitencourt, Julia; Peralta-Álvarez, Marco Polo; Wilkie, Morven; Jacobs, Ashley; Wright, Daniel; Salman Almujri, Salem; Li, Shuailin; Harris, Stephanie A; Smith, Steven G; Elias, Sean C; White, Andrew D; Satti, Iman; Sharpe, Sally S; O'Shea, Matthew K; McShane, Helen; Tanner, Rachel