SARS-CoV-2 prefusion spike protein stabilized by six rather than two prolines is more potent for inducing antibodies that neutralize viral variants of concern
由六个脯氨酸而非两个脯氨酸稳定的SARS-CoV-2融合前刺突蛋白能更有效地诱导产生中和病毒变异株的抗体。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2110105119
Lu, Mijia; Chamblee, Michelle; Zhang, Yuexiu; Ye, Chengjin; Dravid, Piyush; Park, Jun-Gyu; Mahesh, K C; Trivedi, Sheetal; Murthy, Satyapramod; Sharma, Himanshu; Cassady, Cole; Chaiwatpongsakorn, Supranee; Liang, Xueya; Yount, Jacob S; Boyaka, Prosper N; Peeples, Mark E; Martinez-Sobrido, Luis; Kapoor, Amit; Li, Jianrong