日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A vesicular Warburg effect: Aerobic glycolysis occurs on axonal vesicles for local NAD+ recycling and transport

囊泡瓦堡效应:有氧糖酵解发生在轴突囊泡上,以进行局部 NAD+ 回收和运输

Maximilian Mc Cluskey, Hervé Dubouchaud, Anne-Sophie Nicot, Frédéric Saudou

Mono- and Biallelic Inactivation of Huntingtin Gene in Patient-Specific Induced Pluripotent Stem Cells Reveal HTT Roles in Striatal Development and Neuronal Functions

患者特异性诱导多能干细胞中亨廷顿基因的单等位基因和双等位基因失活揭示了HTT在纹状体发育和神经元功能中的作用

Morgane Louessard ,Michel Cailleret ,Margot Jarrige ,Julie Bigarreau ,Sophie Lenoir ,Noëlle Dufour ,Maria Rey ,Frédéric Saudou ,Nicole Deglon ,Anselme L Perrier

Customization of the translational complex regulates mRNA-specific translation to control CNS regeneration

翻译复合物的定制化调控mRNA特异性翻译,从而控制中枢神经系统再生。

Julia Schaeffer ,Noemie Vilallongue ,Charlotte Decourt ,Beatrice Blot ,Nacera El Bakdouri ,Elise Plissonnier ,Blandine Excoffier ,Antoine Paccard ,Jean-Jacques Diaz ,Sandrine Humbert ,Frederic Catez ,Frederic Saudou ,Homaira Nawabi ,Stephane Belin

Huntingtin recruits KIF1A to transport synaptic vesicle precursors along the mouse axon to support synaptic transmission and motor skill learning

亨廷顿蛋白招募 KIF1A 沿小鼠轴突运输突触囊泡前体,以支持突触传递和运动技能学习

Hélène Vitet, Julie Bruyère, Hao Xu, Claire Séris, Jacques Brocard, Yah-Sé Abada, Benoît Delatour, Chiara Scaramuzzino, Laurent Venance, Frédéric Saudou

Mitochondrial Bcl-xL promotes brain synaptogenesis by controlling non-lethal caspase activation

线粒体Bcl-xL通过控制非致死性caspase激活来促进脑突触形成。

Trang Thi Minh Nguyen ,Rudy Gadet ,Marine Lanfranchi ,Romane A Lahaye ,Sozerko Yandiev ,Olivier Lohez ,Ivan Mikaelian ,Lea Jabbour ,Ruth Rimokh ,Julien Courchet ,Frédéric Saudou ,Nikolay Popgeorgiev ,Germain Gillet

Huntingtin regulates calcium fluxes in skeletal muscle

亨廷顿蛋白调节骨骼肌中的钙通量

Mathilde Chivet, Maximilian McCluskey, Anne Sophie Nicot, Julie Brocard, Mathilde Beaufils, Diane Giovannini, Benoit Giannesini, Brice Poreau, Jacques Brocard, Sandrine Humbert, Frédéric Saudou, Julien Fauré, Isabelle Marty

Controlled Tau Cleavage in Cells Reveals Abnormal Localizations of Tau Fragments

细胞内受控 Tau 裂解揭示 Tau 片段的异常定位

Anne Fourest-Lieuvin, Angélique Vinit, Béatrice Blot, Anthime Perrot, Eric Denarier, Frédéric Saudou, Isabelle Arnal

Calcineurin and huntingtin form a calcium-sensing machinery that directs neurotrophic signals to the nucleus

钙调神经磷酸酶和亨廷顿蛋白形成一种钙传感机制,将神经营养信号引导至细胞核

Chiara Scaramuzzino, Emeline C Cuoc, Patrick Pla, Sandrine Humbert, Frédéric Saudou

Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuit

皮质纹状体回路中Disc1/亨廷顿蛋白介导的Bdnf转运调控感觉运动门控

Jaaro-Peled, Hanna; Kumar, Sunil; Hughes, Dalton; Sumitomo, Akiko; Kim, Sun-Hong; Zoubovsky, Sandra; Hirota-Tsuyada, Yuki; Zala, Diana; Bruyere, Julie; Katz, Brittany M; Huang, Beverly; Flores, Rafael 3rd; Narayan, Soumya; Hou, Zhipeng; Economides, Aris N; Hikida, Takatoshi; Wetsel, William C; Deisseroth, Karl; Mori, Susumu; Brandon, Nicholas J; Tanaka, Motomasa; Ishizuka, Koko; Houslay, Miles D; Saudou, Frédéric; Dzirasa, Kafui; Sawa, Akira; Tomoda, Toshifumi

A pathogenic proteolysis-resistant huntingtin isoform induced by an antisense oligonucleotide maintains huntingtin function

由反义寡核苷酸诱导产生的具有致病性、抗蛋白水解能力的亨廷顿蛋白亚型可维持亨廷顿蛋白的功能。

Kim, Hyeongju; Lenoir, Sophie; Helfricht, Angela; Jung, Taeyang; Karneva, Zhana K; Lee, Yejin; Beumer, Wouter; van der Horst, Geert B; Anthonijsz, Herma; Buil, Levi Cm; van der Ham, Frits; Platenburg, Gerard J; Purhonen, Pasi; Hebert, Hans; Humbert, Sandrine; Saudou, Frédéric; Klein, Pontus; Song, Ji-Joon