日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The A, B, C, D's of replicative DNA polymerase fidelity: utilizing high-throughput single-molecule sequencing to understand the molecular basis for DNA polymerase accuracy

复制型DNA聚合酶保真度的A、B、C、D:利用高通量单分子测序了解DNA聚合酶准确性的分子基础

Betancurt-Anzola, Leonardo; O'Connell, Killian C; Potapov, Vladimir; Ong, Jennifer L; Tanner, Nathan A; Sauguet, Ludovic; Zatopek, Kelly M

Ancestral [Fe-S] biogenesis system SMS has a unique mechanism of cluster assembly and sulfur utilization

祖先[Fe-S]生物合成系统SMS具有独特的簇组装和硫利用机制

Dussouchaud, Macha; Martinez-Carranza, Markel; Garcia, Pierre-Simon; Clémancey, Martin; Blondin, Geneviève; Betton, Jean Michel; Haouz, Ahmed; Gribaldo, Simonetta; Ollagnier de Choudens, Sandrine; Sauguet, Ludovic; Mechaly, Ariel; Barras, Frédéric

Crystal structures of monomeric BsmI restriction endonuclease reveal coordinated sequential cleavage of two DNA strands

单体BsmI限制性内切酶的晶体结构揭示了两条DNA链的协调顺序切割。

Sieskind, Rémi; Missoury, Sophia; Madru, Clément; Commenge, Isciane; Niogret, Germain; Hollenstein, Marcel; Rondelez, Yannick; Sauguet, Ludovic; Haouz, Ahmed; Legrand, Pierre; Delarue, Marc

The universal Sua5/TsaC family evolved different mechanisms for the synthesis of a key tRNA modification

通用的Sua5/TsaC家族进化出了不同的机制来合成一种关键的tRNA修饰。

Pichard-Kostuch, Adeline; Da Cunha, Violette; Oberto, Jacques; Sauguet, Ludovic; Basta, Tamara

Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel

五聚体配体门控离子通道的药理学相关细胞外位点与单羧酸盐和二羧酸盐结合的结构证据

Fourati, Zaineb; Sauguet, Ludovic; Delarue, Marc

Structure of the DP1-DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases.

DP1-DP2 PolD 复合物与 DNA 结合的结构及其对 DNA 和 RNA 聚合酶进化史的意义

Raia Pierre, Carroni Marta, Henry Etienne, Pehau-Arnaudet Gérard, Brûlé Sébastien, Béguin Pierre, Henneke Ghislaine, Lindahl Erik, Delarue Marc, Sauguet Ludovic

Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel

静电学、质子传感器以及调控质子门控五聚体离子通道GLIC门控转换的网络

Hu, Haidai; Ataka, Kenichi; Menny, Anaïs; Fourati, Zaineb; Sauguet, Ludovic; Corringer, Pierre-Jean; Koehl, Patrice; Heberle, Joachim; Delarue, Marc

Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation

由碱性pH值调控的五聚体离子通道的晶体结构显示出一个完全开放的孔道,并确定了一个用于调节的腔体。

Hu, Haidai; Nemecz, Ákos; Van Renterghem, Catherine; Fourati, Zaineb; Sauguet, Ludovic; Corringer, Pierre-Jean; Delarue, Marc

Structural Basis for Xenon Inhibition in a Cationic Pentameric Ligand-Gated Ion Channel

阳离子五聚体配体门控离子通道中氙抑制的结构基础

Sauguet, Ludovic; Fourati, Zeineb; Prangé, Thierry; Delarue, Marc; Colloc'h, Nathalie

Allosteric and hyperekplexic mutant phenotypes investigated on an α1 glycine receptor transmembrane structure

对α1甘氨酸受体跨膜结构的变构和超惊厥突变表型进行了研究

Moraga-Cid, Gustavo; Sauguet, Ludovic; Huon, Christèle; Malherbe, Laurie; Girard-Blanc, Christine; Petres, Stéphane; Murail, Samuel; Taly, Antoine; Baaden, Marc; Delarue, Marc; Corringer, Pierre-Jean