日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Three Versus 6 Months of Adjuvant Oxaliplatin-Fluoropyrimidine Chemotherapy for Colorectal Cancer: Final Results of SCOT-An International, Randomized, Phase III, Noninferiority Trial

结直肠癌辅助奥沙利铂-氟尿嘧啶化疗3个月与6个月的比较:SCOT国际随机III期非劣效性试验的最终结果

Iveson, Timothy; Saunders, Mark P; Kelly, Caroline; Kerr, Rachel S; Cassidy, Jim; Hollander, Niels Henrik; Tabernero, Josep; Haydon, Andrew; Glimelius, Bengt; Harkin, Andrea; Allan, Karen; McQueen, John; Pearson, Sarah; Boyd, Kathleen A; Briggs, Andrew H; Waterston, Ashita; Medley, Louise; Ellis, Richard; Dhadda, Amandeep S; Harrison, Mark; Falk, Stephen; Rees, Charlotte; Olesen, Rene K; Propper, David; Bridgewater, John; Azzabi, Ashraf; Cunningham, David; Hickish, Tamas; Gollins, Simon; Wasan, Harpreet S; Church, David; Domingo, Enric

AquIRE reveals the mechanisms of clinically induced RNA damage and the conservation and dynamics of glycoRNAs

AquIRE揭示了临床诱导的RNA损伤机制以及糖RNA的保守性和动态性

Zhang, Zijian; Kotopanova, Zornitsa Vasileva; Dang, Kexin; Kong, Xiangxu; Simms, Nicole; Yuen, Tin Wai; Lam, Lan; Beadle, Lauren Forbes; Hilton, Emma; Qureshi, Taqdees; Coppola, Marianna; Holmes, Callum David; Kan, Kwan Ting; Ashe, Mark; Gallois, Patrick; Ashe, Hilary; Braun, Michael; Saunders, Mark; Sutton, Paul; Thornton, David J; Knight, John R P

Maintaining oxaliplatin therapy after hypersensitivity reactions: real-world experience with a desensitisation protocol

过敏反应后维持奥沙利铂治疗:脱敏方案的真实世界经验

Christodoulis, Eleftherios; Vlachostergios, Panagiotis J; Connell, Jacqueline; Williams, Joseph; Hasan, Jurjees; Mansoor, Wasat; Mullamitha, Saifee; Hubner, Richard A; Braun, Michael; Saunders, Mark P; Marti Marti, Francisca; Angelakas, Angelos; Waddell, Tom; Alam, Nooreen; Kamposioras, Konstantinos

Exploring perceptual disparities: A study on the level of understanding of colorectal cancer care among patients and healthcare professionals

探索认知差异:一项关于患者和医疗保健专业人员对结直肠癌护理理解水平的研究

Christodoulis, Eleftherios; Ntellas, Panagiotis; Simpson, Lilly; Dadouli, Katerina; Connell, Jacqueline; Lim, Kok Haw Jonathan; Williams, Joseph; Hasan, Jurjees; Adamou, Marios; Mullamitha, Saifee; Anderson, Daniel; Marti Marti, Francisca; Braun, Michael; Saunders, Mark; Gillham, Tess; Kamposioras, Konstantinos

Tumor control and immune activation through palliative irradiation and ATR inhibition, PATRIOT Part C: a phase Ib trial.

通过姑息性放射治疗和 ATR 抑制来控制肿瘤和激活免疫,PATRIOT C 部分:一项 Ib 期试验

Dillon Magnus T, Patin Emmanuel C, Mohammed Kabir, Guevara Jeane, Smith Simon A, Dean Emma, Soliman Heba, Nenclares Pablo, Ryugenji Motoko, Northcote Davina, Shah Neel, Grove Lorna, Lord Christopher J, Pettit Stephen, Tall Matt, Swales Karen E, Banerji Udai, Melcher Alan A, Saunders Mark, Forster Martin D, Harrington Kevin J

Final results of ANICCA-Class II, a single arm, open-label phase II trial assessing nivolumab in tissue-specific class II expressing metastatic microsatellite stable colorectal cancer, with a parallel assessment of the immunoscore-immune checkpoint as a predictive biomarker for single-agent anti-PD-1.

ANICCA-Class II 的最终结果是一项单臂、开放标签的 II 期试验,旨在评估 nivolumab 在组织特异性 II 类表达转移性微卫星稳定型结直肠癌中的疗效,同时平行评估免疫评分-免疫检查点作为单药抗 PD-1 的预测生物标志物。

Middleton Gary, Gaskell Charlotte, Savage Joshua, Bridgewater John, Ross Paul, Saunders Mark, Palmer Daniel, Plummer Ruth, Clive Sally, Coyle Vicky, Thomas Anne, Cunningham David, Taniere Phillipe, Billingham Lucinda

Prognostic and Predictive Value of Immunoscore in Stage III Colorectal Cancer: Pooled Analysis of Cases From the SCOT and IDEA-HORG Studies

免疫评分在 III 期结直肠癌中的预后和预测价值:SCOT 和 IDEA-HORG 研究病例的汇总分析

Domingo, Enric; Kelly, Caroline; Hay, Jennifer; Sansom, Owen; Maka, Noori; Oien, Karin; Iveson, Tim; Saunders, Mark; Kerr, Rachel; Tomlinson, Ian; Edwards, Joanne; Harkin, Andrea; Nowak, Marta; Koelzer, Viktor; Easton, Alistair; Boukovinas, Ioannis; Moustou, Eleni; Messaritakis, Ippokratis; Chondrozoumaki, Maria; Karagianni, Michaela; Pagès, Franck; Arnoux, Fanny; Lautard, Christelle; Lovera, Yoann; Boquet, Isabelle; Catteau, Aurélie; Galon, Jérôme; Souglakos, Ioannis; Church, David N

Time From Colorectal Cancer Surgery to Adjuvant Chemotherapy: Post Hoc Analysis of the SCOT Randomized Clinical Trial

从结直肠癌手术到辅助化疗的时间:SCOT随机临床试验的事后分析

Gögenur, Mikail; Rosen, Andreas Weinberger; Iveson, Timothy; Kerr, Rachel S; Saunders, Mark P; Cassidy, Jim; Tabernero, Josep; Haydon, Andrew; Glimelius, Bengt; Harkin, Andrea; Allan, Karen; Pearson, Sarah; Boyd, Kathleen A; Briggs, Andrew H; Waterston, Ashita; Medley, Louise; Ellis, Richard; Dhadda, Amandeep S; Harrison, Mark; Falk, Stephen; Rees, Charlotte; Olesen, Rene K; Propper, David; Bridgewater, John; Azzabi, Ashraf; Cunningham, David; Hickish, Tamas; Gollins, Simon; Wasan, Harpreet S; Kelly, Caroline; Gögenur, Ismail; Holländer, Niels Henrik

Durable responses to ATR inhibition with ceralasertib in tumors with genomic defects and high inflammation

在具有基因组缺陷和高炎症水平的肿瘤中,使用ceralasertib抑制ATR可产生持久疗效。

Dillon, Magnus T; Guevara, Jeane; Mohammed, Kabir; Patin, Emmanuel C; Smith, Simon A; Dean, Emma; Jones, Gemma N; Willis, Sophie E; Petrone, Marcella; Silva, Carlos; Thway, Khin; Bunce, Catey; Roxanis, Ioannis; Nenclares, Pablo; Wilkins, Anna; McLaughlin, Martin; Jayme-Laiche, Adoracion; Benafif, Sarah; Nintos, Georgios; Kwatra, Vineet; Grove, Lorna; Mansfield, David; Proszek, Paula; Martin, Philip; Moore, Luiza; Swales, Karen E; Banerji, Udai; Saunders, Mark P; Spicer, James; Forster, Martin D; Harrington, Kevin J

Single-cell AI-based detection and prognostic and predictive value of DNA mismatch repair deficiency in colorectal cancer

基于单细胞人工智能的结直肠癌DNA错配修复缺陷检测及其预后和预测价值

Nowak, Marta; Jabbar, Faiz; Rodewald, Ann-Katrin; Gneo, Luciana; Tomasevic, Tijana; Harkin, Andrea; Iveson, Tim; Saunders, Mark; Kerr, Rachel; Oein, Karin; Maka, Noori; Hay, Jennifer; Edwards, Joanne; Tomlinson, Ian; Sansom, Owen; Kelly, Caroline; Pezzella, Francesco; Kerr, David; Easton, Alistair; Domingo, Enric; Koelzer, Viktor H; Church, David N