日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Regulatory T cells constrain T cells of shared specificity to enforce tolerance during infection.

调节性T细胞限制具有共同特异性的T细胞,从而在感染期间增强免疫耐受性

Klawon David E J, Pagane Nicole, Walker Matthew T, Ganci Nicole K, Miller Christine H, Gai Eric, Rodriguez Donald M, Ryan-Payseur Bridgett K, Duncombe Ryan K, Adams Erin J, Maienschein-Cline Mark, Freitag Nancy E, Germain Ronald N, Wong Harikesh S, Savage Peter A

The endogenous repertoire harbors self-reactive CD4(+) T cell clones that adopt a follicular helper T cell-like phenotype at steady state

内源性T细胞库中含有自身反应性CD4(+) T细胞克隆,这些克隆在稳态下会呈现滤泡辅助性T细胞样表型。

Lee, Victoria; Rodriguez, Donald M; Ganci, Nicole K; Zeng, Sharon; Ai, Junting; Chao, Jaime L; Walker, Matthew T; Miller, Christine H; Klawon, David E J; Schoenbach, Mary H; Kennedy, Domenick E; Maienschein-Cline, Mark; Socci, Nicholas D; Clark, Marcus R; Savage, Peter A

A robust and interpretable gene signature for predicting the lymph node status of primary T1/T2 oral cavity squamous cell carcinoma

一种稳健且可解释的基因特征,用于预测原发性T1/T2期口腔鳞状细胞癌的淋巴结状态

Ghantous, Yasmin; Omar, Mohamed; Broner, Esther Channah; Agrawal, Nishant; Pearson, Alexander T; Rosenberg, Ari J; Mishra, Vasudha; Singh, Alka; El-Naaj, Imad Abu; Savage, Peter A; Sidransky, David; Marchionni, Luigi; Izumchenko, Evgeny

Immune profiles in primary squamous cell carcinoma of the head and neck

头颈部原发性鳞状细胞癌的免疫特征

Saloura, Vassiliki; Izumchenko, Evgeny; Zuo, Zhixiang; Bao, Riyue; Korzinkin, Michael; Ozerov, Ivan; Zhavoronkov, Alex; Sidransky, David; Bedi, Atul; Hoque, Mohammad O; Koeppen, Hartmut; Keck, Michaela K; Khattri, Arun; London, Nyall; Kotlov, Nikita; Fatima, Aiman; Vougiouklakis, Theodore; Nakamura, Yusuke; Lingen, Mark; Agrawal, Nishant; Savage, Peter A; Kron, Stephen; Kline, Justin; Kowanetz, Marcin; Seiwert, Tanguy Y

Negligible Role for Deletion Mediated by cDC1 in CD8(+) T Cell Tolerance

cDC1介导的缺失在CD8(+) T细胞耐受中作用微乎其微

MacNabb, Brendan W; Kline, Douglas E; Albright, Annie R; Chen, Xiufen; Leventhal, Daniel S; Savage, Peter A; Kline, Justin

Unlocking the Complexities of Tumor-Associated Regulatory T Cells

揭开肿瘤相关调节性T细胞的复杂性

Chao, Jaime L; Savage, Peter A

Dendritic Cells Coordinate the Development and Homeostasis of Organ-Specific Regulatory T Cells

树突状细胞协调器官特异性调节性T细胞的发育和稳态

Leventhal, Daniel S; Gilmore, Dana C; Berger, Julian M; Nishi, Saki; Lee, Victoria; Malchow, Sven; Kline, Douglas E; Kline, Justin; Vander Griend, Donald J; Huang, Haochu; Socci, Nicholas D; Savage, Peter A

Ablation of B7-H3 but Not B7-H4 Results in Highly Increased Tumor Burden in a Murine Model of Spontaneous Prostate Cancer

在自发性前列腺癌小鼠模型中,B7-H3 基因敲除而非 B7-H4 基因敲除会导致肿瘤负荷显著增加。

Kreymborg, Katharina; Haak, Stefan; Murali, Rajmohan; Wei, Joyce; Waitz, Rebecca; Gasteiger, Georg; Savage, Peter A; van den Brink, Marcel R M; Allison, James P

Recipient NK cell inactivation and intestinal barrier loss are required for MHC-matched graft-versus-host disease

受体NK细胞失活和肠道屏障破坏是MHC匹配的移植物抗宿主病所必需的。

Nalle, Sam C; Kwak, H Aimee; Edelblum, Karen L; Joseph, Nora E; Singh, Gurminder; Khramtsova, Galina F; Mortenson, Eric D; Savage, Peter A; Turner, Jerrold R

Shaping the repertoire of tumor-infiltrating effector and regulatory T cells

塑造肿瘤浸润效应T细胞和调节性T细胞的谱系

Savage, Peter A; Leventhal, Daniel S; Malchow, Sven