日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A shear stress-responsive pathway in monocytes drives cardiopulmonary bypass-induced inflammation via spectrin/RAF1/store-operated calcium entry.

单核细胞中的剪切应力反应通路通过血影蛋白/RAF1/储存操纵的钙离子内流驱动体外循环诱导的炎症。

Li Weiming, Tu Lan N, Hsieh Lance, Smith Julian R, Yeh Yi-Ting, Sinyagin Anthony, Evans Eric G B, Ghassemian Majid, Timms Andrew, Charette Kevin, Mauchley David, McMullan Michael, Bohuta Lyubomyr, Greene Christina, Regier Mary C, Del Alamo Juan Carlos, Savan Ram, Nigam Vishal

Sequence Diversity in the 3' Untranslated Region of Alphavirus Modulates IFIT2-Dependent Restriction in a Cell Type-Dependent Manner

甲病毒3'非翻译区序列多样性以细胞类型依赖的方式调节IFIT2依赖性限制

Hickson, Sarah E; Brekke, Eden; Schwerk, Johannes; Saluhke, Indraneel; Zaver, Shivam; Woodward, Joshua; Savan, Ram; Hyde, Jennifer L

Synthetic RIG-I-Agonist RNA Induces Death of Hepatocellular Carcinoma Cells.

合成的RIG-I激动剂RNA诱导肝细胞癌细胞死亡

Ulloa Brittany S, Barber-Axthelm Isaac, Berube Bryan, Duthie Malcolm, Reed Steve, Savan Ram, Gale Michael Jr

Comprehensive Atomic-Scale 3D Viral-Host Protein Interactomes Enable Dissection of Key Mechanisms and Evolutionary Processes Underlying Viral Pathogenesis

全面的原子尺度三维病毒-宿主蛋白相互作用组图谱有助于解析病毒致病机制的关键机制和进化过程。

Li, Le; Roy, Priyamvada Guha; Liu, Yilin; Zhang, Zizhao; Xiong, Dapeng; Savan, Ram; Gokhale, Nandan S; Schang, Luis M; Das, Jishnu; Yu, Haiyuan

Identification of host lncRNAs that impact Venezuelan equine encephalitis virus replication.

鉴定影响委内瑞拉马脑炎病毒复制的宿主lncRNA

Behnia Mahgol, Ye Chunyan, Somfleth Kim, Oyebamiji Olufunmilola M, Brayer Kathryn J, Guo Yan, Ness Scott A, Savan Ram, Bradfute Steven B

Plasmacytoid dendritic cells in the intestine preferentially produce interferon lambda at homeostasis contributing to tonic localized innate immune responses.

肠道中的浆细胞样树突状细胞在体内平衡状态下优先产生干扰素λ,从而促进持续的局部先天免疫反应

Constant David A, Van Winkle Jacob A, Norwood Philip A, Mishra Gargi, Meyer Kimberly A, Laney Margaret E, Madden Shelby R, Griffith Alec, Rodrigues Patrick Fernandes, Savan Ram, Nice Timothy J

Cellular RNA interacts with MAVS to promote antiviral signaling

细胞RNA与MAVS相互作用以促进抗病毒信号传导

Gokhale, Nandan S; Sam, Russell K; Somfleth, Kim; Thompson, Matthew G; Marciniak, Daphnée M; Smith, Julian R; Genoyer, Emmanuelle; Eggenberger, Julie; Chu, Lan H; Park, Moonhee; Dvorkin, Steve; Oberst, Andrew; Horner, Stacy M; Ong, Shao-En; Gale, Michael Jr; Savan, Ram

Innate immunity and interferon in SARS-CoV-2 infection outcome

先天免疫和干扰素在SARS-CoV-2感染结局中的作用

Savan, Ram; Gale, Michael Jr

Host-specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome

CARD8炎症小体对冠状病毒和微小核糖核酸病毒的宿主特异性识别

Tsu, Brian V; Agarwal, Rimjhim; Gokhale, Nandan S; Kulsuptrakul, Jessie; Ryan, Andrew P; Fay, Elizabeth J; Castro, Lennice K; Beierschmitt, Christopher; Yap, Christina; Turcotte, Elizabeth A; Delgado-Rodriguez, Sofia E; Vance, Russell E; Hyde, Jennifer L; Savan, Ram; Mitchell, Patrick S; Daugherty, Matthew D

Innate Immunity in Hepatitis C Virus Infection

丙型肝炎病毒感染中的先天免疫

Schwerk, Johannes; Negash, Amina; Savan, Ram; Gale, Michael Jr