日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

RO4938581, a GABA(A)-α5 negative allosteric modulator rescued behavioral and EEG phenotypes of a mouse model of Dup15q syndrome

RO4938581 是一种 GABA(A)-α5 负变构调节剂，可改善 Dup15q 综合征小鼠模型的行为和脑电图表型。

期刊:Molecular Psychiatry
影响因子:10.1
doi:10.1038/s41380-025-03247-y
Nakagawa, Ryoko; Nani, Francesca; Hipp, Joerg F; Honer, Michael; Knoflach, Frederic; Gasser, Rodolfo; Ozmen, Laurence; Tamada, Kota; Fjeldskaar, Fatiha; Takacs, Livia; Vautheny, Audrey; Morairty, Stephen R; Saxe, Michael; Takumi, Toru; Hernandez, Maria-Clemencia
神经科学
发表日期：2026
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Preclinical pharmacology of alogabat: a novel GABA(A)-α5 positive allosteric modulator targeting neurodevelopmental disorders with impaired GABA(A) signaling

alogabat 的临床前药理学研究：一种新型 GABA(A)-α5 正向变构调节剂，靶向治疗 GABA(A) 信号传导受损的神经发育障碍

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2025.1626078
Cecere, Giuseppe; Ballard, Theresa M; Knoflach, Frederic; Honer, Michael; Hipp, Joerg F; Garces, Pilar; Mueggler, Thomas; Künnecke, Basil; Bruns, Andreas; Prinssen, Eric P; Schoenenberger, Philipp; Janz, Philipp; Redondo, Roger; Biemans, Barbara; Knust, Henner; Olivares-Morales, Andrés; Brigo, Alessandro; Schulz, Jan Michael; Bertrand, Daniel; Saxe, Michael; O'Connor, Eoin C; Hernandez, Maria-Clemencia
信号转导
发育与干细胞
神经科学
发表日期：2025
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Pharmacological Enhancement of Adult Hippocampal Neurogenesis Improves Behavioral Pattern Separation in Young and Aged Male Mice

药物增强成年海马神经发生可改善年轻和老年雄性小鼠的行为模式分离能力

期刊:Biological Psychiatry: Global Open Science
影响因子:3.7
doi:10.1016/j.bpsgos.2024.100419
Chang, Wei-Li; Tegang, Karly; Samuels, Benjamin A; Saxe, Michael; Wichmann, Juergen; David, Denis J; David, Indira Mendez; Augustin, Angélique; Fischer, Holger; Golling, Sabrina; Lamerz, Jens; Roth, Doris; Graf, Martin; Zoffmann, Sannah; Santarelli, Luca; Jagasia, Ravi; Hen, René
Hippo
发表日期：2025
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Enhanced Social Dominance and Altered Neuronal Excitability in the Prefrontal Cortex of Male KCC2b Mutant Mice

雄性KCC2b突变小鼠前额叶皮层社会支配性增强和神经元兴奋性改变

期刊:Autism Research
影响因子:5.6
doi:10.1002/aur.2098
Anacker, Allison M J; Moran, Jacqueline T; Santarelli, Sara; Forsberg, C Gunnar; Rogers, Tiffany D; Stanwood, Gregg D; Hall, Benjamin J; Delpire, Eric; Veenstra-VanderWeele, Jeremy; Saxe, Michael D
神经科学
发表日期：2019
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Allelic frequencies of the hs1.2 enhancer within the immunoglobulin heavy chain region in Dayton, Ohio patients screened for celiac disease with duodenal biopsy

俄亥俄州代顿市通过十二指肠活检筛查乳糜泻患者的免疫球蛋白重链区内 hs1.2 增强子的等位基因频率

期刊:Digestive and Liver Disease
影响因子:4
doi:10.1016/j.dld.2017.03.023
Jing Liu, Rebecca A Law, Paul G Koles, Jonathan C Saxe, Michael Bottomley, Courtney E W Sulentic
免疫
发表日期：2017
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Comprehensive Analysis of the 16p11.2 Deletion and Null Cntnap2 Mouse Models of Autism Spectrum Disorder.

对自闭症谱系障碍的 16p11.2 缺失和 Cntnap2 基因敲除小鼠模型进行综合分析

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0134572
Brunner Daniela, Kabitzke Patricia, He Dansha, Cox Kimberly, Thiede Lucinda, Hanania Taleen, Sabath Emily, Alexandrov Vadim, Saxe Michael, Peles Elior, Mills Alea, Spooren Will, Ghosh Anirvan, Feliciano Pamela, Benedetti Marta, Luo Clayton Alice, Biemans Barbara
神经科学
自闭症
Mouse
发表日期：2015
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