日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Immunoscore immune checkpoint using spatial quantitative analysis of CD8 and PD-L1 markers is predictive of the efficacy of anti- PD1/PD-L1 immunotherapy in non-small cell lung cancer

利用CD8和PD-L1标志物的空间定量分析进行免疫检查点评分的免疫评分可预测抗PD-1/PD-L1免疫疗法在非小细胞肺癌中的疗效。

Ghiringhelli, François; Bibeau, Frederic; Greillier, Laurent; Fumet, Jean-David; Ilie, Alis; Monville, Florence; Laugé, Caroline; Catteau, Aurélie; Boquet, Isabelle; Majdi, Amine; Morgand, Erwan; Oulkhouir, Youssef; Brandone, Nicolas; Adam, Julien; Sbarrato, Thomas; Kassambara, Alboukadel; Fieschi, Jacques; Garcia, Stéphane; Lepage, Anne Laure; Tomasini, Pascale; Galon, Jérôme

Analytical validation of the Immunoscore and its associated prognostic value in patients with colon cancer

对免疫评分及其在结肠癌患者中的预后价值进行分析验证

Marliot, Florence; Chen, Xiaoyi; Kirilovsky, Amos; Sbarrato, Thomas; El Sissy, Carine; Batista, Luciana; Van den Eynde, Marc; Haicheur-Adjouri, Nacilla; Anitei, Maria-Gabriela; Musina, Ana-Maria; Scripcariu, Viorel; Lagorce-Pagès, Christine; Hermitte, Fabienne; Galon, Jérôme; Fieschi, Jacques; Pagès, Franck

A Bistable Mechanism Mediated by Integrins Controls Mechanotaxis of Leukocytes

整合素介导的双稳态机制控制白细胞的机械趋化性

Alexander Hornung, Thomas Sbarrato, Nicolas Garcia-Seyda, Laurene Aoun, Xuan Luo, Martine Biarnes-Pelicot, Olivier Theodoly, Marie-Pierre Valignat

Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4

霉菌内酯抑制Sec61依赖性转位,使整合应激反应与内质网应激解耦,并通过ATF4的翻译激活驱动细胞毒性。

Ogbechi, Joy; Hall, Belinda S; Sbarrato, Thomas; Taunton, Jack; Willis, Anne E; Wek, Ronald C; Simmonds, Rachel E

RTN3 Is a Novel Cold-Induced Protein and Mediates Neuroprotective Effects of RBM3

RTN3是一种新型的冷诱导蛋白,介导RBM3的神经保护作用。

Bastide, Amandine; Peretti, Diego; Knight, John R P; Grosso, Stefano; Spriggs, Ruth V; Pichon, Xavier; Sbarrato, Thomas; Roobol, Anne; Roobol, Jo; Vito, Davide; Bushell, Martin; von der Haar, Tobias; Smales, C Mark; Mallucci, Giovanna R; Willis, Anne E

An improved analysis methodology for translational profiling by microarray

一种改进的基于微阵列的翻译分析方法

Sbarrato, Thomas; Spriggs, Ruth V; Wilson, Lindsay; Jones, Carolyn; Dudek, Kate; Bastide, Amandine; Pichon, Xavier; Pöyry, Tuija; Willis, Anne E

Suboptimal T-cell receptor signaling compromises protein translation, ribosome biogenesis, and proliferation of mouse CD8 T cells

不理想的 T 细胞受体信号传导会影响蛋白质翻译、核糖体生物合成和小鼠 CD8 T 细胞的增殖

Thomas C J Tan, John Knight, Thomas Sbarrato, Kate Dudek, Anne E Willis, Rose Zamoyska

A ribosome-related signature in peripheral blood CLL B cells is linked to reduced survival following treatment

外周血 CLL B 细胞中的核糖体相关特征与治疗后生存率降低有关

T Sbarrato, E Horvilleur, T Pöyry, K Hill, L C Chaplin, R V Spriggs, M Stoneley, L Wilson, S Jayne, T Vulliamy, D Beck, I Dokal, M J S Dyer, A M Yeomans, G Packham, M Bushell, S D Wagner, A E Willis

The malignant phenotype in breast cancer is driven by eIF4A1-mediated changes in the translational landscape

乳腺癌的恶性表型是由 eIF4A1 介导的翻译格局变化驱动的

A Modelska, E Turro, R Russell, J Beaton, T Sbarrato, K Spriggs, J Miller, S Gräf, E Provenzano, F Blows, P Pharoah, C Caldas, J Le Quesne

A role for eukaryotic initiation factor 4B overexpression in the pathogenesis of diffuse large B-cell lymphoma

真核起始因子 4B 过度表达在弥漫性大 B 细胞淋巴瘤发病机制中的作用

E Horvilleur, T Sbarrato, K Hill, R V Spriggs, M Screen, P J Goodrem, K Sawicka, L C Chaplin, C Touriol, G Packham, K N Potter, S Dirnhofer, A Tzankov, M J S Dyer, M Bushell, M MacFarlane, A E Willis