日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IL-4 mediated TAP2 downregulation is a dominant and reversible mechanism of immune evasion and immunotherapy resistance in non-small cell lung cancer.

IL-4 介导的 TAP2 下调是非小细胞肺癌免疫逃逸和免疫治疗耐药的主要且可逆的机制

Ranjan Kishu, Rajendran Barani Kumar, Deen Imad Ud, Costantini Adrien, de Rodas Miguel Lopez, Desai Shruti S, Scallo Frankie, Gianino Nicole, Ferrone Soldano, Schalper Kurt A

Targeting an essential viral oncoprotein with an IL-7-enhanced mRNA vaccine induces durable immunity to Merkel cell carcinoma

利用IL-7增强的mRNA疫苗靶向一种重要的病毒癌蛋白,可诱导对默克尔细胞癌的持久免疫力。

Alexander Frey ,Kathryn Clulo ,Yuewei Fei ,Therese Cordero Dumit ,Frankie Scallo ,Jerry William Allen ,Emily Chang ,Curtis J Perry ,Lena V Wirth ,Daniel Jacobs ,David A Braun ,Marcus W Bosenberg ,Thuy T Tran ,James Clune ,Harriet M Kluger ,Kelly Olino ,Jeffrey J Ishizuka

mTORC1 activity oscillates throughout the cell cycle, promoting mitotic entry and differentially influencing autophagy induction

mTORC1活性在整个细胞周期中呈周期性波动,促进细胞进入有丝分裂,并对自噬诱导产生不同的影响。

Joshi, Jay N; Lerner, Ariel D; Scallo, Frank; Grumet, Alexandra N; Matteson, Paul; Millonig, James H; Valvezan, Alexander J

mTORC1 activity oscillates throughout the cell cycle promoting mitotic entry and differentially influencing autophagy induction

mTORC1 活性在整个细胞周期中振荡,促进有丝分裂进入并对自噬诱导产生不同的影响

Jay N Joshi, Ariel D Lerner, Frank Scallo, Alexandra N Grumet, Paul Matteson, James H Millonig, Alexander J Valvezan