日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Functional, Biophysical, and Structural Characterization of Human IgG1 and IgG4 Fc Variants with Ablated Immune Functionality.

人类 IgG1 和 IgG4 Fc 变体的功能、生物物理和结构表征及其免疫功能的丧失

Tam Susan H, McCarthy Stephen G, Armstrong Anthony A, Somani Sandeep, Wu Sheng-Jiun, Liu Xuesong, Gervais Alexis, Ernst Robin, Saro Dorina, Decker Rose, Luo Jinquan, Gilliland Gary L, Chiu Mark L, Scallon Bernard J

Correlations between pharmacokinetics of IgG antibodies in primates vs. FcRn-transgenic mice reveal a rodent model with predictive capabilities

灵长类动物与FcRn转基因小鼠体内IgG抗体药代动力学的相关性分析揭示了一种具有预测能力的啮齿动物模型

Tam, Susan H; McCarthy, Stephen G; Brosnan, Kerry; Goldberg, Kenneth M; Scallon, Bernard J

Discovery and mechanism of ustekinumab: a human monoclonal antibody targeting interleukin-12 and interleukin-23 for treatment of immune-mediated disorders

乌司奴单抗的发现及作用机制:一种靶向白细胞介素-12和白细胞介素-23的人源单克隆抗体,用于治疗免疫介导性疾病

Benson, Jacqueline M; Peritt, David; Scallon, Bernard J; Heavner, George A; Shealy, David J; Giles-Komar, Jill M; Mascelli, Mary Ann

Engineering host cell lines to reduce terminal sialylation of secreted antibodies

通过基因工程改造宿主细胞系,以减少分泌抗体的末端唾液酸化。

Naso, Michael F; Tam, Susan H; Scallon, Bernard J; Raju, T Shantha