日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of β-Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions

由制药公司和学术机构组成的联盟对抗结核分枝杆菌的β-内酰胺类抗生素进行鉴定

Gold, Ben; Zhang, Jun; Quezada, Landys Lopez; Roberts, Julia; Ling, Yan; Wood, Madeleine; Shinwari, Wasima; Goullieux, Laurent; Roubert, Christine; Fraisse, Laurent; Bacqué, Eric; Lagrange, Sophie; Filoche-Rommé, Bruno; Vieth, Michal; Hipskind, Philip A; Jungheim, Louis N; Aubé, Jeffrey; Scarry, Sarah M; McDonald, Stacey L; Li, Kelin; Perkowski, Andrew; Nguyen, Quyen; Dartois, Véronique; Zimmerman, Matthew; Olsen, David B; Young, Katherine; Bonnett, Shilah; Joerss, Douglas; Parish, Tanya; Boshoff, Helena I; Arora, Kriti; Barry, Clifton E 3rd; Guijarro, Laura; Anca, Sara; Rullas, Joaquín; Rodríguez-Salguero, Beatriz; Martínez-Martínez, Maria S; Porras-De Francisco, Esther; Cacho, Monica; Barros-Aguirre, David; Smith, Paul; Berthel, Steven J; Nathan, Carl; Bates, Robert H

G protein signaling-biased agonism at the κ-opioid receptor is maintained in striatal neurons.

纹状体神经元中维持着γ-阿片受体的G蛋白信号偏向激动作用

Ho Jo-Hao, Stahl Edward L, Schmid Cullen L, Scarry Sarah M, Aubé Jeffrey, Bohn Laura M

Biased agonists of the kappa opioid receptor suppress pain and itch without causing sedation or dysphoria

κ阿片受体的偏向性激动剂可抑制疼痛和瘙痒,而不会引起镇静或烦躁不安。

Brust, Tarsis F; Morgenweck, Jenny; Kim, Susy A; Rose, Jamie H; Locke, Jason L; Schmid, Cullen L; Zhou, Lei; Stahl, Edward L; Cameron, Michael D; Scarry, Sarah M; Aubé, Jeffrey; Jones, Sara R; Martin, Thomas J; Bohn, Laura M

Synthesis of Kappa Opioid Antagonists Based On Pyrrolo[1,2-α]quinoxalinones Using an N-Arylation/Condensation/Oxidation Reaction Sequence

利用N-芳基化/缩合/氧化反应序列合成基于吡咯并[1,2-α]喹喔啉酮的κ阿片受体拮抗剂

Scarry, Sarah M; Lovell, Kimberly M; Frankowski, Kevin J; Bohn, Laura M; Aubé, Jeffrey