Scasny相关文献与解析，生知库 | 链接生命科学的每一步

Alibayov, Babek; Jop Vidal, Ana G; Murin, Landon; Scasny, Anna; Takeshita, Kenichi; Beeton, Komal; Edwards, Kristin S; Punshon, Tracy; Jackson, Brian P; McDaniel, Larry S; Vidal, Jorge E

肺炎

毒理研究

氧化应激

发表日期：2025

文献求助收藏

Pneumococcal H₂O₂ reshapes mitochondrial function and reprograms host cell metabolism

肺炎链球菌产生的H₂O₂会重塑线粒体功能并重编程宿主细胞代谢。

期刊:mBio

影响因子:4.7

doi:10.1128/mbio.02019-25

Scasny, Anna; Alibayov, Babek; Hoang, Ngoc; Jop Vidal, Ana G; Takeshita, Kenichi; Bautista-Muñoz, Consuelo; Bengten, Eva; Baez, Antonino; Li, Wei; Hosler, Jonathan; Warncke, Kurt; Edwards, Kristin S; Vidal, Jorge E

Pneumococcal H(2)O(2) Reshapes Mitochondrial Function and Reprograms Host Cell Metabolism.

肺炎球菌 H(2)O(2) 重塑线粒体功能并重编程宿主细胞代谢

期刊:

影响因子:

doi:10.1101/2025.05.22.655446

Scasny Anna, Alibayov Babek, Hoang Ngoc, Jop Vidal Ana G, Takeshita Kenichi, Bengten Eva, Baez Antonino, Li Wei, Hosler Jonathan, Warncke Kurt, Edwards Kristin, Vidal Jorge E

Oxidation of hemoproteins by Streptococcus pneumoniae collapses the cell cytoskeleton and disrupts mitochondrial respiration leading to the cytotoxicity of human lung cells

肺炎链球菌对血红蛋白的氧化会导致细胞骨架崩塌，并破坏线粒体呼吸，从而导致人类肺细胞的细胞毒性

期刊:Microbiology Spectrum

影响因子:3.7

doi:10.1128/spectrum.02912-23

Anna Scasny, Babek Alibayov, Faidad Khan, Shambavi J Rao, Landon Murin, Ana G Jop Vidal, Perriann Smith, Wei Li, Kristin Edwards, Kurt Warncke, Jorge E Vidal

Synergistic Protection against Secondary Pneumococcal Infection by Human Monoclonal Antibodies Targeting Distinct Epitopes

针对不同表位的人类单克隆抗体对继发性肺炎球菌感染的协同保护作用

期刊:Journal of Immunology

影响因子:3.6

doi:10.4049/jimmunol.2200349

Aaron D Gingerich ，Fredejah Royer ，Anna L McCormick ，Anna Scasny ，Jorge E Vidal ，Jarrod J Mousa

Oxidation of hemoproteins by Streptococcus pneumoniae collapses the cell cytoskeleton and disrupts mitochondrial respiration leading to cytotoxicity of human lung cells

肺炎链球菌对血红蛋白的氧化作用会破坏细胞骨架，扰乱线粒体呼吸，最终导致人肺细胞毒性。

期刊:

影响因子:

doi:10.1101/2023.06.07.544089

Scasny, Anna; Alibayov, Babek; Khan, Faidad; Rao, Shambavi J; Murin, Landon; Jop Vidal, Ana G; Smith, Perriann; Wei, Li; Edwards, Kristin; Warncke, Kurt; Vidal, Jorge E

Oxidative Reactions Catalyzed by Hydrogen Peroxide Produced by Streptococcus pneumoniae and Other Streptococci Cause the Release and Degradation of Heme from Hemoglobin

肺炎链球菌和其他链球菌产生的过氧化氢催化的氧化反应会导致血红蛋白中血红素的释放和降解。

期刊:Infection and Immunity

影响因子:2.8

doi:10.1128/iai.00471-22

Alibayov, Babek; Scasny, Anna; Khan, Faidad; Creel, Aidan; Smith, Perriann; Vidal, Ana G Jop; Fitisemanu, Fa'alataitaua M; Padilla-Benavides, Teresita; Weiser, Jeffrey N; Vidal, Jorge E

肺炎

发表日期：2022

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Prophylactic Inhibition of Colonization by Streptococcus pneumoniae with the Secondary Bile Acid Metabolite Deoxycholic Acid

利用次级胆汁酸代谢产物脱氧胆酸预防性抑制肺炎链球菌定植

期刊:Infection and Immunity

影响因子:2.8

doi:10.1128/IAI.00463-21

Vidal, Jorge E; Francis, Meg N; A Angulo-Zamudio, Uriel; McDevitt, Erin; Jop Vidal, Ana G; Alibayov, Babek; Scasny, Anna; Wong, Sandy M; Akerley, Brian J; McDaniel, Larry S

Development of the vertebrate retinal direction-selective circuit

脊椎动物视网膜方向选择回路的发育

期刊:Developmental Biology

影响因子:2.1

doi:10.1016/j.ydbio.2021.06.004

Hamilton, Natalie R; Scasny, Andrew J; Kolodkin, Alex L

发育与干细胞

发表日期：2021

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Hydrogen Peroxide Production by Streptococcus pneumoniae Results in Alpha-hemolysis by Oxidation of Oxy-hemoglobin to Met-hemoglobin

肺炎链球菌产生的过氧化氢通过氧化氧合血红蛋白生成高铁血红蛋白，导致α-溶血。

期刊:mSphere

影响因子:3.1

doi:10.1128/mSphere.01117-20

McDevitt, Erin; Khan, Faidad; Scasny, Anna; Thompson, Courtney D; Eichenbaum, Zehava; McDaniel, Larry S; Vidal, Jorge E

肺炎

发表日期：2020

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Heme-mediated selection of encapsulated Streptococcus pneumoniae in the lungs by oxidative stress

氧化应激介导血红素对肺部荚膜型肺炎链球菌的选择

Pneumococcal H₂O₂ reshapes mitochondrial function and reprograms host cell metabolism

肺炎链球菌产生的H₂O₂会重塑线粒体功能并重编程宿主细胞代谢。

Pneumococcal H(2)O(2) Reshapes Mitochondrial Function and Reprograms Host Cell Metabolism.

肺炎球菌 H(2)O(2) 重塑线粒体功能并重编程宿主细胞代谢

Oxidation of hemoproteins by Streptococcus pneumoniae collapses the cell cytoskeleton and disrupts mitochondrial respiration leading to the cytotoxicity of human lung cells

肺炎链球菌对血红蛋白的氧化会导致细胞骨架崩塌，并破坏线粒体呼吸，从而导致人类肺细胞的细胞毒性

Synergistic Protection against Secondary Pneumococcal Infection by Human Monoclonal Antibodies Targeting Distinct Epitopes

针对不同表位的人类单克隆抗体对继发性肺炎球菌感染的协同保护作用

Oxidation of hemoproteins by Streptococcus pneumoniae collapses the cell cytoskeleton and disrupts mitochondrial respiration leading to cytotoxicity of human lung cells

肺炎链球菌对血红蛋白的氧化作用会破坏细胞骨架，扰乱线粒体呼吸，最终导致人肺细胞毒性。

Oxidative Reactions Catalyzed by Hydrogen Peroxide Produced by Streptococcus pneumoniae and Other Streptococci Cause the Release and Degradation of Heme from Hemoglobin

肺炎链球菌和其他链球菌产生的过氧化氢催化的氧化反应会导致血红蛋白中血红素的释放和降解。

Prophylactic Inhibition of Colonization by Streptococcus pneumoniae with the Secondary Bile Acid Metabolite Deoxycholic Acid

利用次级胆汁酸代谢产物脱氧胆酸预防性抑制肺炎链球菌定植

Development of the vertebrate retinal direction-selective circuit

脊椎动物视网膜方向选择回路的发育

Hydrogen Peroxide Production by Streptococcus pneumoniae Results in Alpha-hemolysis by Oxidation of Oxy-hemoglobin to Met-hemoglobin

肺炎链球菌产生的过氧化氢通过氧化氧合血红蛋白生成高铁血红蛋白，导致α-溶血。