日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A study of gene expression in the living human brain

一项关于活体人脑基因表达的研究

Liharska, Lora E; Park, You Jeong; Ziafat, Kimia; Wilkins, Lillian; Silk, Hannah; Linares, Lisa M; Thompson, Ryan C; Vornholt, Eric; Sullivan, Brendan; Cohen, Vanessa; Kota, Prashant; Feng, Claudia; Cheng, Esther; Johnson, Jessica S; Rieder, Marysia-Kolbe; Huang, Jia; Scarpa, Joseph; Polanco, Jairo; Moya, Emily; Hashemi, Alice; Levin, Matthew A; Nadkarni, Girish N; Sebra, Robert; Crary, John F; Schadt, Eric E; Beckmann, Noam D; Kopell, Brian H; Charney, Alexander W

A transcriptional program associated with neurotransmission in the living human brain

与活体人脑神经传递相关的转录程序

Charney, Alexander W; Liharska, Lora E; Vornholt, Eric; Valentine, Alissa; Lund, Anina; Hashemi, Alice; Thompson, Ryan C; Lohrenz, Terry; Johnson, Jessica S; Bussola, Nicole; Cheng, Esther; Park, You Jeong; Qasim, Salman; Aristel, Alisha; Wilkins, Lillian; Ziafat, Kimia; Silk, Hannah; Linares, Lisa M; Sullivan, Brendan; Feng, Claudia; Batten, Seth R; Bang, Dan; Barbosa, Leonardo S; Twomey, Thomas; White, Jason P; Vannucci, Marina; Hadj-Amar, Beniamino; Moya, Emily; Figee, Martijn; Nadkarni, Girish N; Breen, Michael S; Kishida, Kenneth T; Scarpa, Joseph; Schadt, Eric E; Saez, Ignacio; Montague, P Read; Beckmann, Noam D; Kopell, Brian H

A Collection of Patient-Derived Intestinal Organoid Lines Reveals Epithelial Phenotypes Associated with Genetic Drivers of Pediatric Inflammatory Bowel Disease.

一系列患者来源的肠道类器官系揭示了与儿童炎症性肠病遗传驱动因素相关的上皮表型。

Shojaei Jeshvaghani Zahra, Argmann Carmen, de Vries Maaike H, van Es Johan H, Collen Lauren V, Kotlarz Daniel, Sveen Mia, Comella Phillip H, Snapper Scott B, Klein Christoph, Schadt Eric E, Clevers Hans, Mokry Michal, Kuijk Ewart, Nieuwenhuis Edward

Prediction of checkpoint inhibitor immunotherapy efficacy for cancer using routine blood tests and clinical data

利用常规血液检查和临床数据预测癌症免疫检查点抑制剂疗法的疗效

Yoo, Seong-Keun; Fitzgerald, Conall W; Cho, Byuri Angela; Fitzgerald, Bailey G; Han, Catherine; Koh, Elizabeth S; Pandey, Abhinav; Sfreddo, Hannah; Crowley, Fionnuala; Korostin, Michelle Rudshteyn; Debnath, Neha; Leyfman, Yan; Valero, Cristina; Lee, Mark; Vos, Joris L; Lee, Andrew Sangho; Zhao, Karena; Lam, Stanley; Olumuyide, Ezekiel; Kuo, Fengshen; Wilson, Eric A; Hamon, Pauline; Hennequin, Clotilde; Saffern, Miriam; Vuong, Lynda; Hakimi, A Ari; Brown, Brian; Merad, Miriam; Gnjatic, Sacha; Bhardwaj, Nina; Galsky, Matthew D; Schadt, Eric E; Samstein, Robert M; Marron, Thomas U; Gönen, Mithat; Morris, Luc G T; Chowell, Diego

Toward governance of artificial intelligence in pediatric healthcare

迈向儿科医疗保健领域人工智能治理

Richter, Felix; Holmes, Emma; Richter, Florian; Guttmann, Katherine; Duong, Son Q; Gangadharan, Sandeep; Schadt, Eric E; Salmasian, Hojjat; Gelb, Bruce D; Glicksberg, Benjamin S

Milademetan in Advanced Solid Tumors with MDM2 Amplification and Wild-type TP53: Preclinical and Phase II Clinical Trial Results

米拉德美坦治疗MDM2扩增和TP53野生型晚期实体瘤:临床前和II期临床试验结果

Dumbrava, Ecaterina E; Stinchcombe, Thomas E; Gounder, Mrinal; Cote, Gregory M; Hanna, Glenn J; Sumrall, Bradley; Wise-Draper, Trisha M; Kanaan, Mohammed; Duffy, Steven; Sumey, Christopher; Cobb, Patrick; Forbes, Andre; Beckmann, Aviva G; Schadt, Eric E; Ku, Nora; Tirunagaru, Vijaya G; Singh, Kanchan; Pei, Xinyu; Xu, Feng; Doebele, Robert C; Chen, Christopher T

Plasma proteins are integral to gene-regulatory networks acting within and across blood cells, the arterial wall and major metabolic organs

血浆蛋白是基因调控网络的重要组成部分,这些网络作用于血细胞、动脉壁和主要代谢器官内部及之间。

Bankier, Sean; Talukdar, Husain; Khan, Mariyam; Mocci, Giuseppe; Sukhavasi, Katyayani; Hao, Ke; Ma, Angela; Ruusalepp, Arno; Schadt, Eric E; Kovacic, Jason C; Michoel, Tom; Björkegren, Johan Lm

Anti-correlated feature selection prevents false discovery of subpopulations in scRNAseq

反相关特征选择可防止单细胞RNA测序中错误发现亚群。

Tyler, Scott R; Lozano-Ojalvo, Daniel; Guccione, Ernesto; Schadt, Eric E

An algorithm to identify patients aged 0-3 with rare genetic disorders

一种用于识别0-3岁患有罕见遗传疾病患者的算法

Webb, Bryn D; Lau, Lisa Y; Tsevdos, Despina; Shewcraft, Ryan A; Corrigan, David; Shi, Lisong; Lee, Seungwoo; Tyler, Jonathan; Li, Shilong; Wang, Zichen; Stolovitzky, Gustavo; Edelmann, Lisa; Chen, Rong; Schadt, Eric E; Li, Li

Characterizing cell type specific transcriptional differences between the living and postmortem human brain

表征活体和死后人脑细胞类型特异性转录差异

Vornholt, Eric; Liharska, Lora E; Cheng, Esther; Hashemi, Alice; Park, You Jeong; Ziafat, Kimia; Wilkins, Lillian; Silk, Hannah; Linares, Lisa M; Thompson, Ryan C; Sullivan, Brendan; Moya, Emily; Nadkarni, Girish N; Sebra, Robert; Schadt, Eric E; Kopell, Brian H; Charney, Alexander W; Beckmann, Noam D