日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Engineering Decavalent, Sperm-Binding Laminin-IgG Hybrid Antibodies for Potent Non-Hormonal Contraception.

工程化十价精子结合层粘连蛋白-IgG 混合抗体用于强效非激素避孕。

Schaefer Alison, Kushiro Keiichiro, Shrestha Bhawana, Zhu Yong, Panjwani Alysha, Dawson Lauren, Flowers Haley, Vincent Kathleen L, Lai Samuel K

Bispecific Siglec-15/T cell antibody (STAB) activates T cells and suppresses pancreatic ductal adenocarcinoma and non-small cell lung tumors in vivo.

双特异性 Siglec-15/T 细胞抗体 (STAB) 可激活 T 细胞,并在体内抑制胰腺导管腺癌和非小细胞肺癌

Shen Limei, Schaefer Alison, Huckaby Justin, Wolf Whitney, Lai Samuel K

Vaginally-delivered fast-dissolving antibody tablets (FDAT) for on-demand non-hormonal contraception and multi-purpose protection

阴道内快速溶解抗体片(FDAT),用于按需非激素避孕和多用途保护

Kushiro, Keiichiro; Hammers, Scott; Zhu, Yong; Flowers, Haley B; Dawson, Lauren; Panjwani, Alysha; Schaefer, Alison; Quan, David; Gibb, Katherine; McSweeney, Morgan; Cone, Richard; Moench, Thomas; Vincent, Kathleen L; Lai, Samuel K

Preferential apical infection and spread of human metapneumovirus highlights the importance of inhaled delivery of neutralizing monoclonal antibody to treat established infections

人偏肺病毒优先发生于肺尖感染和扩散,凸显了吸入中和单克隆抗体治疗已确诊感染的重要性。

Tiruthani, Karthik; Card, Madison P; Wolf, Whitney; Shen, Limei; Schaefer, Alison; Fritz, Marshall; Okuda, Kenichi; Harkema, Jack R; Mousa, Jarrod J; J Pickles, Raymond; Lai, Samuel K

ZMapp reduces diffusion of Ebola viral particles in fresh human cervicovaginal mucus

ZMapp可减少埃博拉病毒颗粒在新鲜人宫颈阴道粘液中的扩散

Schaefer, Alison; Yang, Bing; Schroeder, Holly A; Harit, Dimple; Humphry, Mike S; Zeitlin, Larry; Whaley, Kevin J; Ravel, Jacques; Fischer, William A; Lai, Samuel K

Broadly neutralizing antibodies consistently trap HIV-1 in fresh cervicovaginal mucus from select individuals

广谱中和抗体能够持续地从特定个体的宫颈阴道新鲜粘液中捕获 HIV-1。

Schaefer, Alison; Yang, Bing; Schroeder, Holly A; Harit, Dimple; Humphry, Mike S; Ravel, Jacques; Lai, Samuel K

The biophysical principles underpinning muco-trapping functions of antibodies

抗体黏液捕获功能的生物物理原理

Schaefer, Alison; Lai, Samuel K

Engineering sperm-binding IgG antibodies for the development of an effective nonhormonal female contraception

工程改造精子结合IgG抗体,以开发一种有效的非激素女性避孕方法

Shrestha, Bhawana; Schaefer, Alison; Zhu, Yong; Saada, Jamal; Jacobs, Timothy M; Chavez, Elizabeth C; Olmsted, Stuart S; Cruz-Teran, Carlos A; Vaca, Gabriela Baldeon; Vincent, Kathleen; Moench, Thomas R; Lai, Samuel K

Engineering Polymer-Binding Bispecific Antibodies for Enhanced Pretargeted Delivery of Nanoparticles to Mucus-Covered Epithelium

工程化聚合物结合双特异性抗体用于增强纳米颗粒向黏液覆盖上皮的预靶向递送

Huckaby, Justin T; Parker, Christina L; Jacobs, Tim M; Schaefer, Alison; Wadsworth, Daniel; Nguyen, Alexander; Wang, Anting; Newby, Jay; Lai, Samuel K

Convolutional neural networks automate detection for tracking of submicron-scale particles in 2D and 3D

卷积神经网络可自动检测二维和三维空间中亚微米级颗粒的跟踪情况。

Newby, Jay M; Schaefer, Alison M; Lee, Phoebe T; Forest, M Gregory; Lai, Samuel K