日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Concurrent Inhibition of ERK and Farnesyltransferase Suppresses the Growth of HRAS Mutant Head and Neck Squamous Cell Carcinoma

同时抑制ERK和法尼基转移酶可抑制HRAS突变型头颈部鳞状细胞癌的生长

Javaid, Sehrish; Schaefer, Antje; Goodwin, Craig M; Nguyen, Victoria V; Massey, Frances L; Pierobon, Mariaelena; Gambrell-Sanders, Da'Jhnae; Waters, Andrew M; Lambert, Kathryn N; Diehl, J Nathaniel; Hobbs, G Aaron; Wood, Kris C; Petricoin, Emanuel F; Der, Channing J; Cox, Adrienne D

Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer

RHOA 功能获得性突变促进弥漫性胃癌中黏着斑激酶的激活和依赖性

Zhang, Haisheng; Schaefer, Antje; Wang, Yichen; Hodge, Richard G; Blake, Devon R; Diehl, J Nathaniel; Papageorge, Alex G; Stachler, Matthew D; Liao, Jennifer; Zhou, Jin; Wu, Zhong; Akarca, Fahire G; de Klerk, Leonie K; Derks, Sarah; Pierobon, Mariaelena; Hoadley, Katherine A; Wang, Timothy C; Church, George; Wong, Kwok-Kin; Petricoin, Emanuel F; Cox, Adrienne D; Lowy, Douglas R; Der, Channing J; Bass, Adam J

The molecular basis for immune dysregulation by the hyperactivated E62K mutant of the GTPase RAC2.

GTPase RAC2 过度激活的 E62K 突变体导致免疫失调的分子基础

Arrington Megan E, Temple Brenda, Schaefer Antje, Campbell Sharon L

A local VE-cadherin and Trio-based signaling complex stabilizes endothelial junctions through Rac1

局部VE-钙黏蛋白和Trio信号复合物通过Rac1稳定内皮细胞连接。

Timmerman, Ilse; Heemskerk, Niels; Kroon, Jeffrey; Schaefer, Antje; van Rijssel, Jos; Hoogenboezem, Mark; van Unen, Jakobus; Goedhart, Joachim; Gadella, Theodorus W J Jr; Yin, Taofei; Wu, Yi; Huveneers, Stephan; van Buul, Jaap D

A genomic screen identifies Dsk2p and Rad23p as essential components of ER-associated degradation

基因组筛选鉴定出Dsk2p和Rad23p是内质网相关降解的关键组分。

Medicherla, Balasubrahmanyam; Kostova, Zlatka; Schaefer, Antje; Wolf, Dieter H