日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Loss of epigenetic information as a cause of mammalian aging

表观遗传信息的丢失是哺乳动物衰老的原因之一

Jae-Hyun Yang ,Motoshi Hayano ,Patrick T Griffin ,João A Amorim ,Michael S Bonkowski ,John K Apostolides ,Elias L Salfati ,Marco Blanchette ,Elizabeth M Munding ,Mital Bhakta ,Yap Ching Chew ,Wei Guo ,Xiaojing Yang ,Sun Maybury-Lewis ,Xiao Tian ,Jaime M Ross ,Giuseppe Coppotelli ,Margarita V Meer ,Ryan Rogers-Hammond ,Daniel L Vera ,Yuancheng Ryan Lu ,Jeffrey W Pippin ,Michael L Creswell ,Zhixun Dou ,Caiyue Xu ,Sarah J Mitchell ,Abhirup Das ,Brendan L O'Connell ,Sachin Thakur ,Alice E Kane ,Qiao Su ,Yasuaki Mohri ,Emi K Nishimura ,Laura Schaevitz ,Neha Garg ,Ana-Maria Balta ,Meghan A Rego ,Meredith Gregory-Ksander ,Tatjana C Jakobs ,Lei Zhong ,Hiroko Wakimoto ,Jihad El Andari ,Dirk Grimm ,Raul Mostoslavsky ,Amy J Wagers ,Kazuo Tsubota ,Stephen J Bonasera ,Carlos M Palmeira ,Jonathan G Seidman ,Christine E Seidman ,Norman S Wolf ,Jill A Kreiling ,John M Sedivy ,George F Murphy ,Richard E Green ,Benjamin A Garcia ,Shelley L Berger ,Philipp Oberdoerffer ,Stuart J Shankland ,Vadim N Gladyshev ,Bruce R Ksander ,Andreas R Pfenning ,Luis A Rajman ,David A Sinclair

Emerging Role of Translational Digital Biomarkers Within Home Cage Monitoring Technologies in Preclinical Drug Discovery and Development

转化数字生物标志物在家庭笼监测技术中于临床前药物发现和开发中的新兴作用

Baran, Szczepan W; Bratcher, Natalie; Dennis, John; Gaburro, Stefano; Karlsson, Eleanor M; Maguire, Sean; Makidon, Paul; Noldus, Lucas P J J; Potier, Yohann; Rosati, Giorgio; Ruiter, Matt; Schaevitz, Laura; Sweeney, Patrick; LaFollette, Megan R

Continuous, Automated Breathing Rate and Body Motion Monitoring of Rats With Paraquat-Induced Progressive Lung Injury

对百草枯诱导进行性肺损伤大鼠进行连续、自动呼吸频率和身体运动监测

Baran, Szczepan W; Gupta, Ayan Das; Lim, Maria A; Mathur, Ashwini; Rowlands, David J; Schaevitz, Laura R; Shanmukhappa, Shiva K; Walker, Dana B

Automated and Continuous Monitoring of Animal Welfare through Digital Alerting

通过数字警报实现动物福利的自动化和持续监测

Do, Johnny P; Defensor, Erwin B; Ichim, Christine V; Lim, Maria A; Mechanic, Jordan A; Rabe, Mark D; Schaevitz, Laura R

Circulating microRNA and automated motion analysis as novel methods of assessing chemotherapy-induced peripheral neuropathy in mice

循环microRNA和自动运动分析作为评估小鼠化疗诱导周围神经病变的新方法

Peng, Qinghai; Mechanic, Jordan; Shoieb, Ahmed; Pardo, Ingrid D; Schaevitz, Laura; Fenyk-Melody, Judith; Vitsky, Allison; Boucher, Magalie; Somps, Chris; Cook, Jon C; Liu, Chang-Ning

Retrospective Analysis of the Effects of Identification Procedures and Cage Changing by Using Data from Automated, Continuous Monitoring

利用自动化连续监测数据对识别程序和笼具更换的影响进行回顾性分析

Lim, Maria A; Defensor, Erwin B; Mechanic, Jordan A; Shah, Puja P; Jaime, Evelyn A; Roberts, Clifford R; Hutto, David L; Schaevitz, Laura R

Development of the Digital Arthritis Index, a Novel Metric to Measure Disease Parameters in a Rat Model of Rheumatoid Arthritis

数字关节炎指数的开发:一种用于测量类风湿性关节炎大鼠模型疾病参数的新指标

Lim, Maria A; Louie, Brenton; Ford, Daniel; Heath, Kyle; Cha, Paulyn; Betts-Lacroix, Joe; Lum, Pek Yee; Robertson, Timothy L; Schaevitz, Laura

Gld2-catalyzed 3' monoadenylation of miRNAs in the hippocampus has no detectable effect on their stability or on animal behavior

海马中 Gld2 催化的 miRNA 3' 单腺苷酸化对其稳定性或动物行为没有可检测到的影响。

Mansur, Fernanda; Ivshina, Maria; Gu, Weifeng; Schaevitz, Laura; Stackpole, Emily; Gujja, Sharvari; Edwards, Yvonne J K; Richter, Joel D

Corticothalamic Axons Are Essential for Retinal Ganglion Cell Axon Targeting to the Mouse Dorsal Lateral Geniculate Nucleus

皮质丘脑轴突对于视网膜神经节细胞轴突靶向小鼠背外侧膝状体核至关重要

Shanks, James A; Ito, Shinya; Schaevitz, Laura; Yamada, Jena; Chen, Bin; Litke, Alan; Feldheim, David A

Preclinical research in Rett syndrome: setting the foundation for translational success

雷特综合征的临床前研究:为转化医学的成功奠定基础

Katz, David M; Berger-Sweeney, Joanne E; Eubanks, James H; Justice, Monica J; Neul, Jeffrey L; Pozzo-Miller, Lucas; Blue, Mary E; Christian, Diana; Crawley, Jacqueline N; Giustetto, Maurizio; Guy, Jacky; Howell, C James; Kron, Miriam; Nelson, Sacha B; Samaco, Rodney C; Schaevitz, Laura R; St Hillaire-Clarke, Coryse; Young, Juan L; Zoghbi, Huda Y; Mamounas, Laura A