日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Directed evolution of novel AAV capsids for enhanced delivery to mouse and human Schwann cells

定向进化新型AAV衣壳以增强其向小鼠和人雪旺氏细胞的递送。

Carneiro, Ana D; Nisanov, Alan M; Lee, Hyuncheol; Schaffer, David V

Nickase fidelity drives EvolvR-mediated diversification in mammalian cells

切口酶的保真度驱动哺乳动物细胞中 EvolvR 介导的多样化

Hurtado, Juan E; Schieferecke, Adam J; Halperin, Shakked O; Guan, John; Aidlen, Dylan; Schaffer, David V; Dueber, John E

Advances in AAV capsid engineering: Integrating rational design, directed evolution and machine learning

AAV衣壳工程的进展:整合理性设计、定向进化和机器学习

Nisanov, Alan M; Rivera de Jesús, Julio A; Schaffer, David V

Adeno-associated virus serotype 9 structural heterogeneity and stability characterized by charge detection mass spectrometry

利用电荷检测质谱法表征腺相关病毒9型血清型的结构异质性和稳定性

Miller, Zachary M; Lin, Li F; Schaffer, David V; Williams, Evan R

The Application of DNA Viruses to Biotechnology

DNA病毒在生物技术中的应用

Schieferecke, Adam J; Kuxhausen Ralph, Nadia; Schaffer, David V

Multimodal evaluation of network activity and optogenetic interventions in human hippocampal slices.

对人类海马切片中的网络活动和光遗传学干预进行多模态评估

Andrews John P, Geng Jinghui, Voitiuk Kateryna, Elliott Matthew A T, Shin David, Robbins Ash, Spaeth Alex, Wang Albert, Li Lin, Solis Daniel, Keefe Matthew G, Sevetson Jessica L, Rivera de Jesús Julio A, Donohue Kevin C, Larson H Hanh, Ehrlich Drew, Auguste Kurtis I, Salama Sofie, Sohal Vikaas, Sharf Tal, Haussler David, Cadwell Cathryn R, Schaffer David V, Chang Edward F, Teodorescu Mircea, Nowakowski Tomasz Jan

Spectrin mediates 3D-specific matrix stress-relaxation response in neural stem cell lineage commitment

Spectrin介导神经干细胞谱系定向过程中三维特异性基质应力松弛反应。

Qiao, Eric; Baek, Jieung; Fulmore, Camille; Song, Myoung; Kim, Taek-Soo; Kumar, Sanjay; Schaffer, David V

Evolving membrane-associated accessory protein variants for improved adeno-associated virus production

进化膜相关辅助蛋白变体以提高腺相关病毒的生产效率

Schieferecke, Adam J; Lee, Hyuncheol; Chen, Aleysha; Kilaru, Vindhya; Krish Williams, Justin; Schaffer, David V

Computationally guided AAV engineering for enhanced gene delivery

利用计算机引导的AAV工程改造增强基因递送

Guo, Jingxuan; Lin, Li F; Oraskovich, Sydney V; Rivera de Jesús, Julio A; Listgarten, Jennifer; Schaffer, David V

Mechanosensitive stem cell fate choice is instructed by dynamic fluctuations in activation of Rho GTPases

机械敏感性干细胞的命运选择是由Rho GTP酶激活的动态波动所决定的。

Sampayo, Rocío G; Sakamoto, Mason; Wang, Madeline; Kumar, Sanjay; Schaffer, David V