日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A mammalian, glutaminase-free asparaginase enhances venetoclax activity in preclinical AML models with chromosome 7 deletion

一种不含谷氨酰胺酶的哺乳动物天冬酰胺酶可增强维奈托克在染色体 7 缺失的临床前 AML 模型中的活性

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2025.1606239
Majid, Dhabya; Wang, Zhe; Schalk, Amanda M; Yuan, Bin; Tatarata, Qi Zhang; Root, Jessica L; Garza, Araceli Isabella; Yassouf, Mhd Yousuf; Gamal, Basant T; Feri-Borgogno, Sammy; Nguyen, Annie Hoai; Konopleva, Marina; Peeters, Evelien; Su, Ying; Reville, Patrick K; Ravandi-Kashani, Farhad; Lavie, Arnon; Abbas, Hussein A
发表日期：2025
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A human-like glutaminase-free asparaginase is highly efficacious in ASNS(low) leukemia and solid cancer mouse xenograft models.

人类样无谷氨酰胺酶的天冬酰胺酶在 ASNS(low) 白血病和实体癌小鼠异种移植模型中具有很高的疗效

期刊:Cancer Letters
影响因子:10.1
doi:10.1016/j.canlet.2024.217404
Van Trimpont Maaike, Schalk Amanda M, Hofkens Kenneth, Peeters Evelien, T'Sas Sara, Vandemeulebroecke Katrien, Su Ying, De Loera Ashley, Garcia Alyssa, Chen Hui, Lammens Tim, Van Vlierberghe Pieter, Goossens Steven, Lavie Arnon
肿瘤
白血病
Mouse
发表日期：2024
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In vivo stabilization of a less toxic asparaginase variant leads to a durable antitumor response in acute leukemia

体内稳定毒性较低的天冬酰胺酶变体可导致急性白血病产生持久的抗肿瘤反应。

期刊:Haematologica
影响因子:7.9
doi:10.3324/haematol.2022.281390
Van Trimpont, Maaike; Schalk, Amanda M; De Visser, Yanti; Nguyen, Hien Anh; Reunes, Lindy; Vandemeulebroecke, Katrien; Peeters, Evelien; Su, Ying; Lee, Hyun; Lorenzi, Philip L; Chan, Wai-Kin; Mondelaers, Veerle; De Moerloose, Barbara; Lammens, Tim; Goossens, Steven; Van Vlierberghe, Pieter; Lavie, Arnon
白血病
肿瘤
毒理研究
肿瘤免疫
发表日期：2023
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Discovery of human-like L-asparaginases with potential clinical use by directed evolution.

通过定向进化发现具有潜在临床应用价值的类人L-天冬酰胺酶

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-017-10758-4
Rigouin Coraline, Nguyen Hien Anh, Schalk Amanda M, Lavie Arnon
免疫/内分泌
发表日期：2017
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