日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Ex vivo long-term expansion of human hematopoietic stem and progenitor cells as a tool for modeling vector integration sites and clonality.

体外长期扩增人类造血干细胞和祖细胞作为模拟载体整合位点和克隆性的工具。

期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-026-07700-6
Fleischauer Jenni, John-Neek Philipp, Ha Teng-Cheong, Mansel Friederike, Kosanke Maike, Selich Anton, Hagedorn Maike, Bastone Antonella Lucía, Schinke Maximilian, Dziadek Violetta, Dittrich-Breiholz Oliver, von Kaisenberg Constantin, Schambach Axel, Rothe Michael
细胞生物学
发育与干细胞
干细胞
发表日期：2026
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Successful treatment of transfusion-dependent β-thalassemia: multiple paths to reach potential cure

成功治疗输血依赖型β-地中海贫血：实现潜在治愈的多条途径

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-025-02135-9
Morgan, Michael; Schambach, Axel
代谢
贫血
发表日期：2025
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Pharmacological and pre-clinical safety profile of rSIV.F/HN, a hybrid lentiviral vector for cystic fibrosis gene therapy

rSIV.F/HN（一种用于囊性纤维化基因治疗的混合慢病毒载体）的药理学和临床前安全性概况

期刊:European Respiratory Journal
影响因子:21
doi:10.1183/13993003.01683-2023
Moiseenko, Alena; Sinadinos, Anthony; Sergijenko, Ana; Pineault, Kyriel; Saleh, Aarash; Nekola, Konradin; Strang, Nathalie; Eleftheraki, Anastasia; Boyd, A Christopher; Davies, Jane C; Gill, Deborah R; Hyde, Stephen C; McLachlan, Gerry; Rath, Tim; Rothe, Michael; Schambach, Axel; Hobbie, Silke; Schuler, Michael; Maier, Udo; Thomas, Matthew J; Mennerich, Detlev; Schmidt, Manfred; Griesenbach, Uta; Alton, Eric W F W; Kreuz, Sebastian
微生物学
基因治疗
发表日期：2025
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Combination of targeted pharmacotherapy and immunotherapy with anti-CD19 CAR NK cells in acute lymphoblastic leukemia

靶向药物治疗联合抗CD19 CAR NK细胞免疫疗法治疗急性淋巴细胞白血病

期刊:Hemasphere
影响因子:14.6
doi:10.1002/hem3.70238
Kirchhoff, Hanna; Schoenherr, Caroline; Fleischer, Lisa; Schweighart, Elizabeth K; Esser, Ruth; Talbot, Steven R; Schambach, Axel; Koehl, Ulrike; Heidenreich, Olaf; Eder, Matthias; Scherr, Michaela
白血病
细胞生物学
CD19
免疫/内分泌
发表日期：2025
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Functional differences between CLL- and ALL-derived CAR T cells in a 3D tumor microenvironment highlight CXCR4 and IL-10 as potential modulatory targets.

CLL 和 ALL 来源的 CAR T 细胞在 3D 肿瘤微环境中的功能差异凸显了 CXCR4 和 IL-10 作为潜在的调节靶点。

期刊:Hemasphere
影响因子:14.6
doi:10.1002/hem3.70279
Dingfelder Janin, Aigner Michael, Lindacher Jana, Lukas Pascal, Flamann Cindy, Nusser Gina, Zimmermann Katharina, Schambach Axel, Graw Frederik, Völkl Simon, Bruns Heiko, Krumbholz Manuela, Haibach Martina, Wilke Jochen, Mackensen Andreas, Lutzny-Geier Gloria
细胞生物学
IL-10
CXCR4
肿瘤微环境
发表日期：2025
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IFN-γ-Induced CD317 Tethers Extracellular Vesicles to Mesenchymal Stromal Cells Interfering With Immune Modulation.

IFN-γ诱导的CD317将细胞外囊泡锚定到间充质基质细胞上，从而干扰免疫调节

期刊:Journal of Extracellular Vesicles
影响因子:14.5
doi:10.1002/jev2.70155
Selich Anton, Weisskoeppel Luisa, Hass Ralf, Hegermann Jan, Schwarzer Adrian, von Kaisenberg Constantin, Schambach Axel, Rothe Michael
细胞生物学
CD3
CD31
囊泡
发表日期：2025
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Base edited "universal" donor CAR T-cell strategies for acute myeloid leukaemia

针对急性髓系白血病的基于基础编辑的“通用”供体CAR T细胞策略

期刊:Leukemia
影响因子:13.4
doi:10.1038/s41375-025-02720-5
Kadirkamanathan, Renuka; Georgiadis, Christos; Kloos, Arnold; Joshi, Akshay; Etuk, Annie; Preece, Roland; Gough, Oliver; Schambach, Axel; Sauer, Martin; Heuser, Michael; Qasim, Waseem
T细胞
白血病
T细胞
细胞生物学
免疫/内分泌
发表日期：2025
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Somatic hypermutation shapes the viral escape profile of SARS-CoV-2 neutralising antibodies.

体细胞高频突变影响 SARS-CoV-2 中和抗体的病毒逃逸特性

期刊:EBioMedicine
影响因子:10.8
doi:10.1016/j.ebiom.2025.105770
Bruhn Matthias, Obara Maureen, Gonzalez-Hernandez Mariana, Reineking Wencke, Salam Abdus, Mirolo Monica, Hinrichs Imke, Mergani AhmedElmontaser, Bartsch Yannic, Schambach Axel, Zimmer Gert, Baumgärtner Wolfgang, Osterhaus Albert D M E, Kalinke Ulrich
细胞生物学
Viral
发表日期：2025
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Engineering a bacterial toxin deaminase from the DYW-family into a novel cytosine base editor for plants and mammalian cells

将DYW家族的细菌毒素脱氨酶改造为一种新型胞嘧啶碱基编辑器，用于植物和哺乳动物细胞。

期刊:Genome Biology
影响因子:9.4
doi:10.1186/s13059-025-03478-w
Zhang, Dingbo; Parth, Fiona; da Silva, Laura Matos; Ha, Teng-Cheong; Schambach, Axel; Boch, Jens
微生物学
细胞生物学
碱基编辑
发表日期：2025
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Anti-FAP CAR-NK cells as a novel targeted therapy against cervical cancer and cancer-associated fibroblasts.

抗FAP CAR-NK细胞作为一种新型靶向疗法，用于治疗宫颈癌和癌相关成纤维细胞。

期刊:Oncoimmunology
影响因子:6.3
doi:10.1080/2162402X.2025.2556714
Polten Robert, Kutle Ivana, Stalp Jan Lennart, Hachenberg Jens, Seyda Ann-Kathrin, Neubert Lavinia, Kamp Jan C, von Kaisenberg Constantin, Schaudien Dirk, Hillemanns Peter, Klapdor Rüdiger, Morgan Michael, Schambach Axel
宫颈癌
细胞生物学
成纤维细胞
FAP
CAR-NK
发表日期：2025
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