Optimized Substrate Positioning Enables Switches in the C-H Cleavage Site and Reaction Outcome in the Hydroxylation-Epoxidation Sequence Catalyzed by Hyoscyamine 6β-Hydroxylase
优化的底物定位可改变莨菪碱6β-羟化酶催化的羟基化-环氧化反应序列中CH键断裂位点和反应结果。
期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.4c04406
Wenger, Eliott S; Martinie, Ryan J; Ushimaru, Richiro; Pollock, Christopher J; Sil, Debangsu; Li, Aaron; Hoang, Nhi; Palowitch, Gavin M; Graham, Brandt P; Schaperdoth, Irene; Burke, Evan J; Maggiolo, Ailiena O; Chang, Wei-Chen; Allen, Benjamin D; Krebs, Carsten; Silakov, Alexey; Boal, Amie K; Bollinger, J Martin Jr
