日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

SARS-Cov-2 Replication in a Blood-Brain Barrier Model Established with Human Brain Microvascular Endothelial Cells Induces Permeability and Disables ACE2-Dependent Regulation of Bradykinin B1 Receptor.

在用人脑微血管内皮细胞建立的血脑屏障模型中，SARS-CoV-2 复制会诱导通透性并破坏 ACE2 依赖的缓激肽 B1 受体调节

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26125540
Coelho Sharton Vinicius Antunes, Souza Gabriela Lisboa E, Bezerra Bruno Braz, Lima Luan Rocha, Correa Isadora Alonso, de Almeida Dalziza Victalina, Silva-Aguiar Rodrigo Pacheco da, Pinheiro Ana Acácia S, Sirois Pierre, Caruso-Neves Celso, Costa Luciana Jesus da, Scharfstein Julio, Arruda Luciana Barros de
细胞生物学
血脑屏障
Human
ACE2
血管生成
发表日期：2025
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Toxoplasma gondii impairs CX3CL1/fractalkine shedding from mouse cortical neurons, leading to microglia activation.

弓形虫会损害小鼠皮层神经元中 CX3CL1/fractalkine 的脱落，从而导致小胶质细胞活化。

期刊:Microbiology Spectrum
影响因子:3.8
doi:10.1128/spectrum.01074-25
de Castro Leonardo Leal, Gomes da Rosa Barbara, Peixoto-Rodrigues Maria Carolina, Revoredo Vicentino Amanda Roberta, Fraga-Junior Vanderlei da Silva, Cascabulho Cynthia M, Diniz Luan Pereira, Benjamim Claudia Farias, Bracko Oliver, Scharfstein Julio, Adesse Daniel
Mouse
细胞生物学
神经科学
胶质细胞
ALK
ACTA
CX3CL1
Fractalkine
发表日期：2025
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Mesocricetus auratus (Golden Syrian Hamster) Experimental Model of SARS-CoV-2 Infection Reveals That Lung Injury Is Associated with Phenotypic Differences Between SARS-CoV-2 Variants.

以金仓鼠（Mesocricetus auratus）为SARS-CoV-2感染实验模型的研究表明，肺损伤与SARS-CoV-2变异株之间的表型差异有关

期刊:Viruses-Basel
影响因子:3.5
doi:10.3390/v17081048
Rodrigues Daniela Del Rosario Flores, da Silva Alexandre Dos Santos, Alves Arthur Daniel Rocha, Rossi Bárbara Araujo, Lima Richard de Almeida, Faria Sarah Beatriz Salvador Castro, Cruz Oswaldo Gonçalves, Muller Rodrigo, Scharfstein Julio, Vicentino Amanda Roberta Revoredo, Matos Aline da Rocha, Dos Santos João Paulo Rodrigues, Manso Pedro Paulo Abreu, Paiva Milla Bezerra, Barreto-Vieira Debora Ferreira, Caldas Gabriela Cardoso, Machado Marcelo Pelajo, Pinto Marcelo Alves
毒理研究
新冠
发表日期：2025
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Brazilian immunology in Caxambu: beyond vaccination, a tribute to the pioneers of basic research in Chagas disease

巴西免疫学在卡桑布：超越疫苗接种，向恰加斯病基础研究的先驱致敬

期刊:Memorias Do Instituto Oswaldo Cruz
影响因子:2.5
doi:10.1590/0074-02760210314chgsb
Scharfstein, Julio
免疫/内分泌
发表日期：2022
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P2Y14 Receptor as a Target for Neutrophilia Attenuation in Severe COVID-19 Cases: From Hematopoietic Stem Cell Recruitment and Chemotaxis to Thrombo-inflammation

P2Y14受体作为重症COVID-19病例中中性粒细胞增多症缓解的靶点：从造血干细胞募集和趋化作用到血栓炎症

期刊:Stem Cell Reviews and Reports
影响因子:4.2
doi:10.1007/s12015-021-10129-7
Lintzmaier Petiz, Lyvia; Glaser, Talita; Scharfstein, Julio; Ratajczak, Mariusz Z; Ulrich, Henning
发育与干细胞
炎症
中性粒细胞
炎症/感染
信号转导
心血管
粒细胞
干细胞
细胞生物学
发表日期：2021
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Mast Cells in Alveolar Septa of COVID-19 Patients: A Pathogenic Pathway That May Link Interstitial Edema to Immunothrombosis

COVID-19 患者肺泡间隔中的肥大细胞：可能将间质水肿与免疫血栓形成联系起来的致病途径

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2020.574862
Motta Junior, Jarbas da Silva; Miggiolaro, Anna Flavia Ribeiro Dos Santos; Nagashima, Seigo; de Paula, Caroline Busatta Vaz; Baena, Cristina Pellegrino; Scharfstein, Julio; de Noronha, Lucia
细胞生物学
肥大细胞
心血管
免疫/内分泌
发表日期：2020
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Mast Cell Coupling to the Kallikrein-Kinin System Fuels Intracardiac Parasitism and Worsens Heart Pathology in Experimental Chagas Disease

肥大细胞与激肽释放酶-激肽系统的偶联促进心内寄生虫感染，并加剧实验性恰加斯病的心脏病理。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2017.00840
Nascimento, Clarissa R; Andrade, Daniele; Carvalho-Pinto, Carla Eponina; Serra, Rafaela Rangel; Vellasco, Lucas; Brasil, Guilherme; Ramos-Junior, Erivan Schnaider; da Mota, Julia Barbalho; Almeida, Larissa Nogueira; Andrade, Marcus V; Correia Soeiro, Maria de Nazaré; Juliano, Luiz; Alvarenga, Patrícia Hessab; Oliveira, Ana Carolina; Sicuro, Fernando Lencastre; de Carvalho, Antônio C Campos; Svensjö, Erik; Scharfstein, Julio
肥大细胞
炎症/感染
心血管
微生物学
心脏病
细胞生物学
发表日期：2017
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Ecotin-like ISP of L. major promastigotes fine-tunes macrophage phagocytosis by limiting the pericellular release of bradykinin from surface-bound kininogens: a survival strategy based on the silencing of proinflammatory G-protein coupled kinin B2 and B1 receptors

利什曼原虫前鞭毛体中的类Ecotin ISP通过限制表面结合的激肽原释放缓激肽来微调巨噬细胞的吞噬作用：一种基于沉默促炎性G蛋白偶联激肽B2和B1受体的生存策略

期刊:Mediators of Inflammation
影响因子:4.2
doi:10.1155/2014/143450
Svensjö, Erik; Nogueira de Almeida, Larissa; Vellasco, Lucas; Juliano, Luiz; Scharfstein, Julio
巨噬细胞
巨噬细胞
信号转导
细胞生物学
免疫/内分泌
发表日期：2014
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Novel family of insect salivary inhibitors blocks contact pathway activation by binding to polyphosphate, heparin, and dextran sulfate

一类新型昆虫唾液抑制剂通过与多聚磷酸盐、肝素和硫酸葡聚糖结合，阻断接触途径的激活。

期刊:Arteriosclerosis Thrombosis and Vascular Biology
影响因子:7.4
doi:10.1161/ATVBAHA.113.302482
Alvarenga, Patricia H; Xu, Xueqing; Oliveira, Fabiano; Chagas, Andrezza C; Nascimento, Clarissa R; Francischetti, Ivo M B; Juliano, Maria A; Juliano, Luiz; Scharfstein, Julio; Valenzuela, Jesus G; Ribeiro, José M C; Andersen, John F
发表日期：2013
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Trypanosoma cruzi invades host cells through the activation of endothelin and bradykinin receptors: a converging pathway leading to chagasic vasculopathy

克氏锥虫通过激活内皮素和缓激肽受体侵入宿主细胞：这是导致恰加斯病血管病变的共同通路。

期刊:British Journal of Pharmacology
影响因子:7.7
doi:10.1111/j.1476-5381.2011.01609.x
Andrade, Daniele; Serra, Rafaela; Svensjö, Erik; Lima, Ana Paula C; Ramos, Erivan S Jr; Fortes, Fabio S; Morandini, Ana Carolina F; Morandi, Verônica; Soeiro, Maria de N; Tanowitz, Herbert B; Scharfstein, Julio
信号转导
细胞生物学
发表日期：2012
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