日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Novel aldo-keto reductase 1C3 inhibitor affects androgen metabolism but not ovarian function in healthy women: a phase 1 study

新型醛酮还原酶 1C3 抑制剂影响健康女性的雄激素代谢,但不影响卵巢功能:一项 1 期研究

Gashaw, Isabella; Reif, Stefanie; Wiesinger, Herbert; Kaiser, Andreas; Zollmann, Frank S; Scheerans, Christian; Grevel, Joachim; Piraino, Paolo; Seidel, Henrik; Peters, Michaele; Rottmann, Antje; Rohde, Beate; Arlt, Wiebke; Hilpert, Jan

Hepatotoxicity of AKR1C3 Inhibitor BAY1128688: Findings from an Early Terminated Phase IIa Trial for the Treatment of Endometriosis

AKR1C3抑制剂BAY1128688的肝毒性:一项早期终止的IIa期治疗子宫内膜异位症试验的结果

Hilpert, Jan; Groettrup-Wolfers, Esther; Kosturski, Hristiyan; Bennett, Laura; Barnes, Catriona L K; Gude, Kerstin; Gashaw, Isabella; Reif, Stefanie; Steger-Hartmann, Thomas; Scheerans, Christian; Solms, Alexander; Rottmann, Antje; Mao, Guangping; Chapron, Charles

Safety, Pharmacodynamics, and Pharmacokinetics of P2X3 Receptor Antagonist Eliapixant (BAY 1817080) in Healthy Subjects: Double-Blind Randomized Study

P2X3受体拮抗剂Eliapixant(BAY 1817080)在健康受试者中的安全性、药效学和药代动力学:双盲随机研究

Friedrich, Christian; Francke, Klaus; Gashaw, Isabella; Scheerans, Christian; Klein, Stefan; Fels, Lueder; Smith, Jaclyn A; Hummel, Thomas; Morice, Alyn

Quantitative Systems Pharmacology Approaches for Immuno-Oncology: Adding Virtual Patients to the Development Paradigm

免疫肿瘤学的定量系统药理学方法:将虚拟病人纳入研发范式

Chelliah, Vijayalakshmi; Lazarou, Georgia; Bhatnagar, Sumit; Gibbs, John P; Nijsen, Marjoleen; Ray, Avijit; Stoll, Brian; Thompson, R Adam; Gulati, Abhishek; Soukharev, Serguei; Yamada, Akihiro; Weddell, Jared; Sayama, Hiroyuki; Oishi, Masayo; Wittemer-Rump, Sabine; Patel, Chirag; Niederalt, Christoph; Burghaus, Rolf; Scheerans, Christian; Lippert, Jörg; Kabilan, Senthil; Kareva, Irina; Belousova, Natalya; Rolfe, Alex; Zutshi, Anup; Chenel, Marylore; Venezia, Filippo; Fouliard, Sylvain; Oberwittler, Heike; Scholer-Dahirel, Alix; Lelievre, Helene; Bottino, Dean; Collins, Sabrina C; Nguyen, Hoa Q; Wang, Haiqing; Yoneyama, Tomoki; Zhu, Andy Z X; van der Graaf, Piet H; Kierzek, Andrzej M

Proposal for defining the relevance of drug accumulation derived from single dose study data for modified release dosage forms

关于如何界定单剂量研究数据中药物蓄积对缓释制剂相关性的提案

Scheerans, Christian; Heinig, Roland; Mueck, Wolfgang

Compliance assessment of ambulatory Alzheimer patients to aid therapeutic decisions by healthcare professionals

对可自由活动的阿尔茨海默病患者进行依从性评估,以辅助医疗保健专业人员的治疗决策

Schwalbe, Oliver; Scheerans, Christian; Freiberg, Ines; Schmidt-Pokrzywniak, Andrea; Stang, Andreas; Kloft, Charlotte