The cell cycle stage of bovine zygotes electroporated with CRISPR/Cas9-RNP affects frequency of Loss-of-heterozygosity editing events
牛受精卵经 CRISPR/Cas9-RNP 电穿孔后的细胞周期阶段会影响杂合性缺失编辑事件的频率。
期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-022-14699-5
Miskel, Dennis; Poirier, Mikhael; Beunink, Luisa; Rings, Franca; Held, Eva; Tholen, Ernst; Tesfaye, Dawit; Schellander, Karl; Salilew-Wondim, Dessie; Blaschka, Carina; Große-Brinkhaus, Christine; Brenig, Bertram; Hoelker, Michael