日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting the major pro-inflammatory interleukin-6-type cytokine receptor gp130 by antagonistic single domain antibodies.

利用拮抗性单域抗体靶向主要的促炎性白细胞介素-6型细胞因子受体gp130

Pudewell Silke, Heuser Julia, Dorogobed Inna, Lipinski Britta, Tran Thi Hong Hue, Metzenmacher Pia, Kunze Richard, Geyer Felix, Zielonka Stefan, Floss Doreen M, Kolmar Harald, Moll Jens M, Scheller Jürgen

Intratumoral Delivery of Genetically Engineered Anti-IL-6 Trans-signaling Therapeutics.

肿瘤内递送基因工程抗IL-6反式信号疗法

Bento Raphaela, Scheller Jürgen, Parekkadan Biju

Interleukin-6, but not the interleukin-6 receptor plays a role in recovery from dextran sodium sulfate-induced colitis.

白细胞介素-6(而非白细胞介素-6受体)在葡聚糖硫酸钠诱导的结肠炎的恢复中发挥作用

Sommer Jan, Engelowski Erika, Baran Paul, Garbers Christoph, Floss Doreen M, Scheller Jürgen

Inhibition of protein kinase II (CK2) prevents induced signal transducer and activator of transcription (STAT) 1/3 and constitutive STAT3 activation.

抑制蛋白激酶 II (CK2) 可阻止诱导信号转导和转录激活因子 (STAT) 1/3 和组成型 STAT3 的激活

Aparicio-Siegmund Samadhi, Sommer Jan, Monhasery Niloufar, Schwanbeck Ralf, Keil Eric, Finkenstädt David, Pfeffer Klaus, Rose-John Stefan, Scheller Jürgen, Garbers Christoph

An interleukin-6 receptor-dependent molecular switch mediates signal transduction of the IL-27 cytokine subunit p28 (IL-30) via a gp130 protein receptor homodimer.

白细胞介素-6受体依赖性分子开关通过gp130蛋白受体同源二聚体介导IL-27细胞因子亚基p28(IL-30)的信号转导

Garbers Christoph, Spudy Björn, Aparicio-Siegmund Samadhi, Waetzig Georg H, Sommer Jan, Hölscher Christoph, Rose-John Stefan, Grötzinger Joachim, Lorenzen Inken, Scheller Jürgen

A disintegrin and metalloprotease (ADAM) 10 and ADAM17 are major sheddases of T cell immunoglobulin and mucin domain 3 (Tim-3).

解整合素和金属蛋白酶 (ADAM) 10 和 ADAM17 是 T 细胞免疫球蛋白和粘蛋白结构域 3 (Tim-3) 的主要脱落酶

Möller-Hackbarth Katja, Dewitz Christin, Schweigert Olga, Trad Ahmad, Garbers Christoph, Rose-John Stefan, Scheller Jürgen