日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Postmortem Associations Between Alzheimer Disease Pathology and Plasma pTau217, GFAP, and NfL in AD and AD-Related Dementias

阿尔茨海默病病理与血浆 pTau217、GFAP 和 NfL 之间的死后关联性研究(AD 及 AD 相关痴呆症)

Kivisäkk, Pia; Fatima, Hadia; Wu, Chao-Yi; Padmanabhan, Nikhil; Romero, Daniel; Gorham, Taron; Weik, Molly; Dodge, Hiroko H; Scherzer, Clemens R; Das, Sudeshna; Chibnik, Lori B; Blacker, Deborah L; Gomez-Isla, Teresa; Oakley, Derek H; Frosch, Matthew P; Hyman, Bradley T; Demos, Catherine; Sigal, George; Wohlstadter, Jacob N; Serrano-Pozo, Alberto; Arnold, Steven E

Integrating Long-Read Structural Variant Analysis with single-nucleus RNA-seq to Elucidate Gene Expression Effects in Disease

将长读长结构变异分析与单核RNA测序相结合,以阐明疾病中的基因表达效应。

Kim, Kwanho; Lin, Zechuan; Simmons, Sean K; Parker, Jacob; Kearney, Matthew; Liao, Zhixiang; Haywood, Nathan; Zhang, Jixiang; Cline, Madison P; Tuncali, Idil; Sharma, Monika; Serrano, Geidy E; Beach, Thomas G; Dong, Xianjun; Popic, Victoria; Scherzer, Clemens R; Levin, Joshua Z

Impact of Y chromosome loss on the risk of Parkinson's disease and progression

Y染色体缺失对帕金森病风险和进展的影响

Wang, Junhao; Chen, Xinyi; Du, Wenxuan; Lin, Cha; Liao, Yu; Corvol, Jean-Christophe; Maple-Grødem, Jodi; Campbell, Meghan C; Elbaz, Alexis; Lesage, Suzanne; Brice, Alexis; Schwarzschild, Michael A; Taba, Pille; Kõks, Sulev; Alves, Guido; Tysnes, Ole-Bjørn; Perlmutter, Joel S; Maiti, Baijayanta; van Hilten, Jacobus J; Barker, Roger A; Williams-Gray, Caroline H; Scherzer, Clemens R; Liu, Ganqiang

Association of Medication Use and 8-Year Mortality Risk in Patients With Parkinson Disease: Drug-Wide Trial Emulation

药物使用与帕金森病患者8年死亡风险的关联:药物范围试验模拟

Tuominen, Julia A; Riise, Trond; Romanowska, Julia; Flores-Torres, Mario H; Cortese, Marianna; Scherzer, Clemens R; Bjornevik, Kjetil; Igland, Jannicke

Genetic Analysis of the X Chromosome Associates Loci with Progression of Parkinson's Disease

X染色体基因分析揭示与帕金森病进展相关的基因位点

Liao, Yu; Wu, Hao; Wang, Junhao; Corvol, Jean-Christophe; Maple-Grødem, Jodi; Campbell, Meghan C; Elbaz, Alexis; Brice, Alexis; Schwarzschild, Michael A; Taba, Pille; Kõks, Sulev; Beach, Thomas G; Alves, Guido; Tysnes, Ole-Bjørn; Perlmutter, Joel S; Maiti, Baijayanta; van Hilten, Jacobus J; Barker, Roger A; Williams-Gray, Caroline H; Scherzer, Clemens R; Liu, Ganqiang

Disease progression strikingly differs in research and real-world Parkinson's populations

研究人群和现实世界中的帕金森病患者,其疾病进展情况存在显著差异。

Beaulieu-Jones, Brett K; Frau, Francesca; Bozzi, Sylvie; Chandross, Karen J; Peterschmitt, M Judith; Cohen, Caroline; Coulovrat, Catherine; Kumar, Dinesh; Kruger, Mark J; Lipnick, Scott L; Fitzsimmons, Lane; Kohane, Isaac S; Scherzer, Clemens R

Correction to: Clinical trial-ready patient cohorts for multiple system atrophy: coupling biospecimen and iPSC banking to longitudinal deep-phenotyping

更正:多系统萎缩的临床试验就绪患者队列:将生物样本和iPSC库与纵向深度表型分析相结合

Ndayisaba, Alain; Pitaro, Ariana T; Willett, Ashlan S; Jones, Kristie A; de Gusmao, Claudio Melo; Olsen, Abby L; Kim, Jisoo; Rissanen, Eero; Woods, Jared K; Srinivasan, Sharan R; Nagy, Anna; Nagy, Amanda; Mesidor, Merlyne; Cicero, Steven; Patel, Viharkumar; Oakley, Derek H; Tuncali, Idil; Taglieri-Noble, Katherine; Clark, Emily C; Paulson, Jordan; Krolewski, Richard C; Ho, Gary P; Hung, Albert Y; Wills, Anne-Marie; Hayes, Michael T; Macmore, Jason P; Warren, Luigi; Bower, Pamela G; Langer, Carol B; Kellerman, Lawrence R; Humphreys, Christopher W; Glanz, Bonnie I; Dielubanza, Elodi J; Frosch, Matthew P; Freeman, Roy L; Gibbons, Christopher H; Stefanova, Nadia; Chitnis, Tanuja; Weiner, Howard L; Scherzer, Clemens R; Scholz, Sonja W; Vuzman, Dana; Cox, Laura M; Wenning, Gregor; Schmahmann, Jeremy D; Gupta, Anoopum S; Novak, Peter; Young, Geoffrey S; Feany, Mel B; Singhal, Tarun; Khurana, Vikram

Genetic screening and metabolomics identify glial adenosine metabolism as a therapeutic target in Parkinson's disease

基因筛查和代谢组学研究发现,神经胶质细胞腺苷代谢是帕金森病治疗的潜在靶点。

Sodders, Maggie J; Avila-Pacheco, Julian; Okorie, Ernest C; Shen, Ming; Kumari, Namrata; Marathi, Archana; Lakhani, Mehek; Bullock, Kevin; Pierce, Kerry; Dennis, Courtney; Jeanfavre, Sarah; Sarkar, Souvarish; Scherzer, Clemens R; Clish, Clary; Olsen, Abby L

Transcriptional pathobiology and multi-omics predictors for Parkinson's disease

帕金森病转录组病理生物学和多组学预测因子

Hu, Ruifeng; Wang, Ruoxuan; Yuan, Jie; Lin, Zechuan; Hutchins, Elizabeth; Landin, Barry; Liao, Zhixiang; Liu, Ganqiang; Scherzer, Clemens R; Dong, Xianjun

Mitochondrial haplogroups and cognitive progression in Parkinson's disease

线粒体单倍群与帕金森病认知进展

Liu, Ganqiang; Ni, Chunming; Zhan, Jiamin; Li, Weimin; Luo, Junfeng; Liao, Zhixiang; Locascio, Joseph J; Xian, Wenbiao; Chen, Ling; Pei, Zhong; Corvol, Jean-Christophe; Maple-Grødem, Jodi; Campbell, Meghan C; Elbaz, Alexis; Lesage, Suzanne; Brice, Alexis; Hung, Albert Y; Schwarzschild, Michael A; Hayes, Michael T; Wills, Anne-Marie; Ravina, Bernard; Shoulson, Ira; Taba, Pille; Kõks, Sulev; Beach, Thomas G; Cormier-Dequaire, Florence; Alves, Guido; Tysnes, Ole-Bjørn; Perlmutter, Joel S; Heutink, Peter; van Hilten, Jacobus J; Barker, Roger A; Williams-Gray, Caroline H; Scherzer, Clemens R