Generation of Alzheimer disease-associated amyloid β42/43 peptide by γ-secretase can be inhibited directly by modulation of membrane thickness.
α-分泌酶产生的阿尔茨海默病相关淀粉样蛋白β42/43肽可通过调节膜厚度直接抑制
期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M112.356659
Winkler Edith, Kamp Frits, Scheuring Johannes, Ebke Amelie, Fukumori Akio, Steiner Harald
