Cyclic peptide inhibitors function as molecular glues to stabilize Gq/11 heterotrimers
环肽抑制剂起到分子胶的作用,稳定Gq/11异源三聚体。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2418398122
Mühle, Jonas; Alenfelder, Judith; Rodrigues, Matthew J; Jürgenliemke, Lars; Guixà-González, Ramon; Grätz, Lukas; Andres, Fabio; Bacchin, Arianna; Hennig, Michael; Schihada, Hannes; Crüsemann, Max; König, Gabriele M; Schertler, Gebhard; Kostenis, Evi; Deupi, Xavier