日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Hyperthermia-targeted rectal delivery of thermosensitive liposomal doxorubicin via intra-arterial and intravenous administration

通过动脉内和静脉内给药，利用高温靶向直肠递送热敏脂质体阿霉素

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2026.1760944
Mikhail, Andrew S; Bakhutashvili, Ivane; Pritchard, William F; Haemmerich, Dieter; Hecht, Rochel; Seifabadi, Reza; Starost, Matthew F; Ashe, Rachel; Schmidt, Keith T; Figg, William D; Wood, Bradford J; Karanian, John W; Mauda-Havakuk, Michal
发表日期：2026
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Tumor-targeted top1 inhibitor delivery with optimized parp inhibition in advanced solid tumors: a phase i trial of gapped scheduling

针对晚期实体瘤，采用优化PARP抑制的肿瘤靶向拓扑异构酶I抑制剂递送：一项采用间隔给药方案的I期临床试验

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-64509-5
Thomas, Anish; Takahashi, Nobuyuki; Oplustil O'Connor, Lenka; Redon, Christophe E; Mohindroo, Chirayu; Sciuto, Linda; Pongor, Lorinc; Schmidt, Keith T; Steinberg, Seth M; Aladjem, Mirit I; Figg, William Douglas; O'Connor, Mark J; Pommier, Yves
PARP
肿瘤
肿瘤免疫
发表日期：2025
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A phase 2 study of single agent ibrutinib for first-line treatment of chronic graft-versus-host disease: A new paradigm and lessons learned

一项针对慢性移植物抗宿主病一线治疗的单药伊布替尼II期研究：新的范式和经验教训

期刊:British Journal of Haematology
影响因子:3.8
doi:10.1111/bjh.20069
El Jurdi, Najla; Holtzman, Noa G; Hishmeh, Rania; Mina, Alain; Schulz, Eduard; Stokes, Anita; Li, Grace; Schmidt, Keith T; Figg, William D; Micheletti, Nicholas; Mays, Jacqueline W; Cowen, Edward W; Pavletic, Steven Z; Pusic, Iskra
发表日期：2025
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Direct Co-Targeting of Bcl-xL and Mcl-1 Exhibits Synergistic Effects in AR-V7-Expressing CRPC Models.

Bcl-xL 和 Mcl-1 的直接共同靶向在 AR-V7 表达的 CRPC 模型中表现出协同效应

期刊:Cancer Research Communications
影响因子:3.3
doi:10.1158/2767-9764.CRC-25-0096
Brim Benjamin C, Leon Andres F, Beatson Erica L, Kindrick Jessica D, Bhadresha Kinjal, Zhang Xiaohu, Napoli Giulia C, Risdon Emily N, Schmidt Keith T, Wilson Kelli M, McKnight Crystal, Beck Erin, Klumpp-Thomas Carleen, Ceribelli Michele, Yin JuanJuan, Sowalsky Adam G, Price Douglas K, Chau Cindy H, Thomas Craig J, Figg William D
CRP
发表日期：2025
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Determination of the pyrrolo[2,3-d] pyrimidine antifolate AGF94 from a preclinical murine study using a simple UHPLC-MS/MS assay

利用简便的超高效液相色谱-串联质谱法（UHPLC-MS/MS）测定临床前小鼠研究中的吡咯并[2,3-d]嘧啶类抗叶酸AGF94。

期刊:Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences
影响因子:2.8
doi:10.1016/j.jchromb.2025.124833
Metz, Tryston T; Ashe, Rachel C; Duncan, Alexis C; Wilner, Ethan C; Schmidt, Keith T; Gudmundsson, Kristbjorn O; Hou, Zhanjun; Gangjee, Aleem; Matherly, Larry H; Kozlov, Serguei V; Figg, William D
多发性硬化症
发表日期：2025
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A Phase 0 Window of Opportunity Trial of LB100, a Protein Phosphatase 2A Inhibitor, in Patients with Recurrent Gliomas

LB100（一种蛋白磷酸酶2A抑制剂）治疗复发性胶质瘤患者的0期机会窗口试验

期刊:Alzheimers & Dementia
影响因子:
doi:10.1101/2025.08.18.25333496
Burton, Eric C; Walker, Erin; Boris, Lisa; Reyes, Jennifer; Fernandez, Kelly; Wall, Kathleen; Wu, Jing; Schmidt, Keith T; Figg, William D; Brown, Desmond A
信号转导
胶质瘤
发表日期：2025
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Pharmacokinetics and pharmacogenomics of ribociclib in black patients with metastatic breast cancer the LEANORA study

LEANORA 研究：利博西尼在转移性乳腺癌黑人患者中的药代动力学和药物基因组学

期刊:NPJ Breast Cancer
影响因子:7.6
doi:10.1038/s41523-024-00692-w
Schlam, Ilana; Smith, D Max; Peer, Cody; Sissung, Tristan; Schmidt, Keith T; Tan, Ming; Chitalia, Ami; Bishopric, Nanette H; Steinberg, Seth; Choo-Wosoba, Hyoyoung; Napoli, Giulia; Gallagher, Christopher; Ashai, Nadia; Whitaker, Kristen; Mainor, Candace; Tiwari, Shruti; Swanson, Nicole; Malloy, Stacy; Isaacs, Claudine; Figg, William Douglas; Swain, Sandra M
肿瘤
肿瘤免疫
乳腺癌
发表日期：2024
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Sitagliptin elevates plasma and CSF incretin levels following oral administration to nonhuman primates: relevance for neurodegenerative disorders

口服西格列汀后，非人灵长类动物血浆和脑脊液中的肠促胰岛素水平升高：与神经退行性疾病的相关性

期刊:Geroscience
影响因子:5.4
doi:10.1007/s11357-024-01120-4
Li, Yazhou; Vaughan, Kelli L; Wang, Yun; Yu, Seong-Jin; Bae, Eun-Kyung; Tamargo, Ian A; Kopp, Katherine O; Tweedie, David; Chiang, Cheng-Chuan; Schmidt, Keith T; Lahiri, Debomoy K; Tones, Michael A; Zaleska, Margaret M; Hoffer, Barry J; Mattison, Julie A; Greig, Nigel H
神经科学
免疫/内分泌
发表日期：2024
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In Silico Re-Optimization of Atezolizumab Dosing Using Population Pharmacokinetic Simulation and Exposure-Response Simulation

利用群体药代动力学模拟和暴露-反应模拟对阿特珠单抗给药方案进行计算机辅助重新优化

期刊:Journal of Clinical Pharmacology
影响因子:2.3
doi:10.1002/jcph.2203
Peer, Cody J; Schmidt, Keith T; Arisa, Oluwatobi; Richardson, William J; Paydary, Koosha; Goldstein, Daniel A; Gulley, James L; Figg, William D; Ratain, Mark J
发表日期：2023
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A Metabolomics Approach for Predicting OATP1B-Type Transporter-Mediated Drug-Drug Interaction Liabilities

利用代谢组学方法预测OATP1B型转运蛋白介导的药物相互作用风险

期刊:Pharmaceutics
影响因子:5.5
doi:10.3390/pharmaceutics14091933
Li, Yang; Jin, Yan; Taheri, Hanieh; Schmidt, Keith T; Gibson, Alice A; Buck, Stefan A J; Eisenmann, Eric D; Mathijssen, Ron H J; Figg, William D; Baker, Sharyn D; Sparreboom, Alex; Hu, Shuiying
OAT
代谢
发表日期：2022
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