Loss of p53 function at late stages of tumorigenesis confers ARF-dependent vulnerability to p53 reactivation therapy
肿瘤发生后期p53功能的丧失赋予了肿瘤细胞ARF依赖性的对p53再激活疗法的易感性。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1910255116
Klimovich, Boris; Mutlu, Samet; Schneikert, Jean; Elmshäuser, Sabrina; Klimovich, Maria; Nist, Andrea; Mernberger, Marco; Timofeev, Oleg; Stiewe, Thorsten