日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacological inhibition of USP18 improves antibacterial responses and the intracellular control of Mycobacterium tuberculosis in macrophages

药理学抑制USP18可改善巨噬细胞的抗菌反应和对结核分枝杆菌的细胞内控制。

Zhang, Qiao; Gong, Zhen; Schnell, Robert; Zhong, Yi; Geurink, Paul P; Lauschke, Volker M; Xie, Jianping; Gastaldello, Stefano; Rottenberg, Martin E

A katE katG double-knockout E. coli strain eliminates the risk of catalase contamination in recombinant proteins

katE katG双敲除大肠杆菌菌株可消除重组蛋白中过氧化氢酶污染的风险。

Scholz, Axel Tobias; Coppo, Lucia; Nolan, Edward; Hernandez, Michaella; Wang, Xuan; Mishra, Pradeep; Schnell, Robert; Pató, Zsuzsanna Anna; Chen, Yifei; Dagnell, Markus; Andor, Attila; Cheng, Qing; Arnér, Elias S J

Alk-Fam150b (augmentor α) expression in the paraventricular nucleus of the mouse hypothalamus at molecular resolution, and its sensitivity to acute stress

在分子分辨率下研究小鼠下丘脑室旁核中 Alk-Fam150b(增强子 α)的表达及其对急性应激的敏感性

Gueissaz, Laurent; Sideromenos, Spyridon; Tretiakov, Evgenii O; Schnell, Robert; Harkany, Tibor

Neuronal activity modulates the expression of secretagogin, a Ca(2+) sensor protein, during mammalian forebrain development.

在哺乳动物前脑发育过程中,神经元活动调节分泌素(一种 Ca(2+) 传感器蛋白)的表达

Hanics János, Tretiakov Evgenii O, Romanov Roman A, Gáspárdy Anna, Hevesi Zsófia, Schnell Robert, Harkany Tibor, Alpár Alán

A hydrophobic groove in secretagogin allows for alternate interactions with SNAP-25 and syntaxin-4 in endocrine tissues

分泌素中的疏水沟槽使其能够与内分泌组织中的 SNAP-25 和突触蛋白-4 发生交替相互作用。

Szodorai, Edit; Hevesi, Zsofia; Wagner, Ludwig; Hökfelt, Tomas G M; Harkany, Tibor; Schnell, Robert

Engineering of Ancestors as a Tool to Elucidate Structure, Mechanism, and Specificity of Extant Terpene Cyclase

利用祖先基因工程技术阐明现存萜烯环化酶的结构、机制和特异性

Schriever, Karen; Saenz-Mendez, Patricia; Rudraraju, Reshma Srilakshmi; Hendrikse, Natalie M; Hudson, Elton P; Biundo, Antonino; Schnell, Robert; Syrén, Per-Olof

Developing a Biased Unmatched Bivalent Ligand (BUmBL) Design Strategy to Target the GPCR Homodimer Allosteric Signaling (cAMP over β-Arrestin 2 Recruitment) Within the Melanocortin Receptors

开发偏向不匹配的二价配体 (BUmBL) 设计策略,以靶向黑皮质素受体内的 GPCR 同型二聚体变构信号传导(cAMP 通过 β-Arrestin 2 募集)

Cody J Lensing, Katie T Freeman, Sathya M Schnell, Robert C Speth, Adam T Zarth, Carrie Haskell-Luevano

Structural and Functional Characterization of the BcsG Subunit of the Cellulose Synthase in Salmonella typhimurium

鼠伤寒沙门氏菌纤维素合成酶BcsG亚基的结构和功能表征

Sun, Lei; Vella, Peter; Schnell, Robert; Polyakova, Anna; Bourenkov, Gleb; Li, Fengyang; Cimdins, Annika; Schneider, Thomas R; Lindqvist, Ylva; Galperin, Michael Y; Schneider, Gunter; Römling, Ute

A Direct in Vivo Comparison of the Melanocortin Monovalent Agonist Ac-His-DPhe-Arg-Trp-NH2 versus the Bivalent Agonist Ac-His-DPhe-Arg-Trp-PEDG20-His-DPhe-Arg-Trp-NH2: A Bivalent Advantage

黑皮质素单价激动剂 Ac-His-DPhe-Arg-Trp-NH2 与二价激动剂 Ac-His-DPhe-Arg-Trp-PEDG20-His-DPhe-Arg-Trp-NH2 的体内直接比较:二价优势

Cody J Lensing, Danielle N Adank, Stacey L Wilber, Katie T Freeman, Sathya M Schnell, Robert C Speth, Adam T Zarth, Carrie Haskell-Luevano

Crystal structure of the flavoenzyme PA4991 from Pseudomonas aeruginosa

铜绿假单胞菌黄素酶 PA4991 的晶体结构

Jacewicz, Agata; Schnell, Robert; Lindqvist, Ylva; Schneider, Gunter