Results From First-in-Human Phase I Study of a Novel CD19-1XX Chimeric Antigen Receptor With Calibrated Signaling in Large B-Cell Lymphoma
一项针对新型CD19-1XX嵌合抗原受体的I期临床试验结果显示，该受体在大B细胞淋巴瘤中具有可校准的信号传导功能。
期刊:Journal of Clinical Oncology
影响因子:41.9
doi:10.1200/JCO-24-02424
Park, Jae H; Palomba, M Lia; Perica, Karlo; Devlin, Sean M; Shah, Gunjan; Dahi, Parastoo B; Lin, Richard J; Salles, Gilles; Scordo, Michael; Nath, Karthik; Valtis, Yannis K; Lynch, Alec; Cathcart, Elizabeth; Zhang, Honglei; Schoder, Heiko; Leithner, Doris; Liotta, Kelly; Yu, Alina; Stocker, Kelsey; Li, Jia; Dey, Agnish; Sellner, Leopold; Singh, Reshma; Sundaresan, Varsha; Tong, Xin; Zhao, Faye; Mansilla-Soto, Jorge; He, Changhao; Meyerson, Joel; Hosszu, Kinga; McAvoy, Devin; Wang, Xiuyan; Rivière, Isabelle; Sadelain, Michel
B细胞
信号转导
淋巴瘤
Human
细胞生物学
CD19
免疫/内分泌
