日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Physiologically based pharmacokinetic modelling to predict artemether and lumefantrine exposure in neonates weighing less than 5 kg treated with artemether-lumefantrine to supplement the clinical data from the CALINA study

基于生理的药代动力学模型预测体重小于5公斤的新生儿接受蒿甲醚-苯芴醇治疗后体内蒿甲醚和苯芴醇的暴露量,以补充CALINA研究的临床数据。

Gu, Helen; Abla, Nada; Venishetty, Vinay Kumar; Schoeberl, Birgit; Zack, Julia; Einolf, Heidi J

Human Cytochrome P450 1, 2, 3 Families as Pharmacogenes with Emphases on Their Antimalarial and Antituberculosis Drugs and Prevalent African Alleles

人类细胞色素P450 1、2、3家族作为药理基因,重点关注其抗疟疾和抗结核药物以及非洲流行等位基因

Chamboko, Chiratidzo R; Veldman, Wayde; Tata, Rolland Bantar; Schoeberl, Birgit; Tastan Bishop, Özlem

Navigating Between Right, Wrong, and Relevant: The Use of Mathematical Modeling in Preclinical Decision Making

在正确、错误和相关性之间找到平衡:数学建模在临床前决策中的应用

Kondic, Anna; Bottino, Dean; Harrold, John; Kearns, Jeffrey D; Musante, C J; Odinecs, Aleksandrs; Ramanujan, Saroja; Selimkhanov, Jangir; Schoeberl, Birgit

Dual targeting of IGF-1R and ErbB3 as a potential therapeutic regimen for ovarian cancer

以IGF-1R和ErbB3为双重靶点治疗卵巢癌的潜在疗法

Camblin, Adam J; Tan, Gege; Curley, Michael D; Yannatos, Isabel; Iadevaia, Sergio; Rimkunas, Victoria; Mino-Kenudson, Mari; Bloom, Troy; Schoeberl, Birgit; Drummond, Daryl C; Lugovskoy, Alexey A; Louis, Chrystal U; Askoxylakis, Vasileios

Tensor clustering with algebraic constraints gives interpretable groups of crosstalk mechanisms in breast cancer

利用代数约束的张量聚类可以解释乳腺癌中串扰机制的分组

Seigal, Anna; Beguerisse-Díaz, Mariano; Schoeberl, Birgit; Niepel, Mario; Harrington, Heather A

Predicting ligand-dependent tumors from multi-dimensional signaling features.

基于多维信号特征预测配体依赖性肿瘤

Hass Helge, Masson Kristina, Wohlgemuth Sibylle, Paragas Violette, Allen John E, Sevecka Mark, Pace Emily, Timmer Jens, Stelling Joerg, MacBeath Gavin, Schoeberl Birgit, Raue Andreas

HER2+ Cancer Cell Dependence on PI3K vs. MAPK Signaling Axes Is Determined by Expression of EGFR, ERBB3 and CDKN1B

HER2+癌细胞对PI3K与MAPK信号通路的依赖性取决于EGFR、ERBB3和CDKN1B的表达。

Kirouac, Daniel C; Du, Jinyan; Lahdenranta, Johanna; Onsum, Matthew D; Nielsen, Ulrik B; Schoeberl, Birgit; McDonagh, Charlotte F

Analysis of growth factor signaling in genetically diverse breast cancer lines

对遗传多样性乳腺癌细胞系中生长因子信号传导的分析

Niepel, Mario; Hafner, Marc; Pace, Emily A; Chung, Mirra; Chai, Diana H; Zhou, Lili; Muhlich, Jeremy L; Schoeberl, Birgit; Sorger, Peter K

Impact of intrinsic affinity on functional binding and biological activity of EGFR antibodies

内在亲和力对EGFR抗体功能性结合和生物活性的影响

Zhou, Yu; Goenaga, Anne-Laure; Harms, Brian D; Zou, Hao; Lou, Jianlong; Conrad, Fraser; Adams, Gregory P; Schoeberl, Birgit; Nielsen, Ulrik B; Marks, James D

An expanding role for cell biologists in drug discovery and pharmacology

细胞生物学家在药物发现和药理学中的作用日益增强

Sorger, Peter K; Schoeberl, Birgit