日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Continuous assay for the dNTP triphosphohydrolase of activated SAMHD1

活化SAMHD1的dNTP三磷酸水解酶的连续测定

期刊:Analytical Biochemistry
影响因子:2.5
doi:10.1016/j.ab.2025.115966
Eskandari, Roozbeh; Groom, Daniel P; Tamura, Ryo; Schramm, Vern L
SAMHD1
发表日期：2026
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Transition State Analysis of SAMHD1 from Primary (18)O, (33)P, and Solvent Kinetic Isotope Effects

利用初级(18)O、(33)P和溶剂动力学同位素效应对SAMHD1进行过渡态分析

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.5c00521
Ghosh, Ananda K; Groom, Daniel P; Schramm, Vern L
SAMHD1
发表日期：2025
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The anti-cancer transition-state inhibitor MTDIA inhibits human MTAP, inducing autophagy in humanized yeast

抗癌过渡态抑制剂MTDIA抑制人MTAP，从而诱导人源化酵母发生自噬。

期刊:Disease Models & Mechanisms
影响因子:3.3
doi:10.1242/dmm.052173
Coorey, Namal V; Tollestrup, Isaac; Bircham, Peter W; Sheridan, Jeffrey P; Evans, Gary B; Schramm, Vern L; Atkinson, Paul H; Munkacsi, Andrew B
MTAP
肿瘤
自噬
肿瘤免疫
发表日期：2025
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Kinetic Mechanism of the Emergent Anticancer Target, Human ADP-ribosyltransferase 1

新兴抗癌靶点——人ADP核糖基转移酶1的动力学机制

期刊:Biochemistry
影响因子:3
doi:10.1021/acs.biochem.5c00105
Groom, Daniel P; Lopacinski, Amanda; Garforth, Scott J; Schramm, Vern L
Human
肿瘤
肿瘤免疫
发表日期：2025
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MAT Gain of Activity Mutation in Helicobacter pylori Is Associated with Resistance to MTAN Transition State Analogues

幽门螺杆菌MAT活性获得性突变与MTAN过渡态类似物的耐药性相关

期刊:ACS Infectious Diseases
影响因子:3.8
doi:10.1021/acsinfecdis.2c00644
Feng, Mu; Namanja-Magliano, Hilda; Rajagopalan, Saranathan; Mishra, Tanmay; Ducati, Rodrigo G; Hirsch, Brett M; Kelly, Libusha; Szymczak, Wendy; Fajardo, Jorge Eduardo; Sidoli, Simone; Fiser, Andras; Jacobs, William R; Schramm, Vern L
发表日期：2023
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Residence Times for Femtomolar and Picomolar Inhibitors of MTANs

MTANs 的飞摩尔级和皮摩尔级抑制剂的停留时间

期刊:Biochemistry
影响因子:3
doi:10.1021/acs.biochem.3c00145
Brown, Morais; Tyler, Peter C; Schramm, Vern L
发表日期：2023
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Isofagomine inhibits multiple TcdB variants and protects mice from Clostridioides difficile induced mortality

异法戈明抑制多种TcdB变体，并保护小鼠免受艰难梭菌感染引起的死亡

期刊:
影响因子:
doi:10.1101/2023.09.19.558375
Paparella, Ashleigh S; Brew, Isabella; Hong, Huynh A; Ferriera, William; Cutting, Simon; Lamiable-Oulaidi, Farah; Popadynec, Michael; Tyler, Peter C; Schramm, Vern L
炎症/感染
发表日期：2023
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Clostridioides difficile TcdB Toxin Glucosylates Rho GTPase by an S(N)i Mechanism and Ion Pair Transition State

艰难梭菌TcdB毒素通过S(N)i机制和离子对过渡态对Rho GTP酶进行葡萄糖基化。

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.2c00408
Paparella, Ashleigh S; Cahill, Sean M; Aboulache, Briana L; Schramm, Vern L
发表日期：2022
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Inhibition and Mechanism of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase

恶性疟原虫次黄嘌呤-鸟嘌呤-黄嘌呤磷酸核糖转移酶的抑制及其机制

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.2c00546
V T Minnow, Yacoba; Suthagar, Kajitha; Clinch, Keith; Ducati, Rodrigo G; Ghosh, Agnidipta; Buckler, Joshua N; Harijan, Rajesh K; Cahill, Sean M; Tyler, Peter C; Schramm, Vern L
发表日期：2022
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Inverse heavy enzyme isotope effects in methylthioadenosine nucleosidases

甲基硫代腺苷核苷酶的反向重酶同位素效应

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2109118118
Brown, Morais; Zoi, Ioanna; Antoniou, Dimitri; Namanja-Magliano, Hilda A; Schwartz, Steven D; Schramm, Vern L
发表日期：2021
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