The PI3K/Akt signaling pathway regulates the expression of Hsp70, which critically contributes to Hsp90-chaperone function and tumor cell survival in multiple myeloma
PI3K/Akt信号通路调控Hsp70的表达，而Hsp70对Hsp90分子伴侣功能以及多发性骨髓瘤中肿瘤细胞的存活至关重要。
期刊:Haematologica
影响因子:7.9
doi:10.3324/haematol.2012.066175
Chatterjee, Manik; Andrulis, Mindaugas; Stühmer, Thorsten; Müller, Elisabeth; Hofmann, Claudia; Steinbrunn, Torsten; Heimberger, Tanja; Schraud, Heike; Kressmann, Stefanie; Einsele, Hermann; Bargou, Ralf C
肿瘤
肿瘤免疫
多发性骨髓瘤
信号转导
PI3K/Akt
骨髓瘤
细胞生物学
肿瘤细胞
