日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

The Engineered Lysin CF-370 Is Active Against Antibiotic-Resistant Gram-Negative Pathogens In Vitro and Synergizes With Meropenem in Experimental Pseudomonas aeruginosa Pneumonia.

工程化赖氨酸 CF-370 在体外对耐抗生素革兰氏阴性病原体具有活性，并且在实验性铜绿假单胞菌肺炎中与美罗培南具有协同作用

期刊:Journal of Infectious Diseases
影响因子:4.5
doi:10.1093/infdis/jiae027
Sauve Karen, Watson Aubrey, Oh Jun T, Swift Steven, Vila-Farres Xavier, Abdelhady Wessam, Xiong Yan Q, LeHoux Dario, Woodnutt Gary, Bayer Arnold S, Schuch Raymond
免疫/内分泌
发表日期：2024
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The Lysin Exebacase Has a Low Propensity for Resistance Development in Staphylococcus aureus and Suppresses the Emergence of Resistance to Antistaphylococcal Antibiotics

赖氨酸酶在金黄色葡萄球菌中产生耐药性的倾向较低，并能抑制抗葡萄球菌抗生素耐药性的出现。

期刊:Microbiology Spectrum
影响因子:3.8
doi:10.1128/spectrum.05261-22
Oh, Jun; Warner, Matthew; Ambler, Jane E; Schuch, Raymond
发表日期：2023
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Rapid bacteriolysis of Staphylococcus aureus by lysin exebacase.

溶菌酶可快速溶解金黄色葡萄球菌

期刊:Microbiology Spectrum
影响因子:3.8
doi:10.1128/spectrum.01906-23
Vila-Farres Xavier, Sauve Karen, Oh Jun, Swift Steven, DeJonge Boudewijn, Ambler Jane E, Schuch Raymond
其它
肠道菌群
发表日期：2023
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In vitro activity of exebacase against methicillin-resistant Staphylococcus aureus biofilms on orthopedic Kirschner wires

体外研究 exebacase 对骨科克氏针上耐甲氧西林金黄色葡萄球菌生物膜的活性

期刊:BMC Research Notes
影响因子:1.7
doi:10.1186/s13104-023-06468-y
Karau, Melissa J; Mandrekar, Jay; Lehoux, Dario; Schuch, Raymond; Cassino, Cara; Patel, Robin
微生物学
发表日期：2023
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Activity of Exebacase (CF-301) against Biofilms Formed by Staphylococcus epidermidis Strains Isolated from Prosthetic Joint Infections

Exebacase (CF-301) 对从人工关节感染中分离的表皮葡萄球菌菌株形成的生物膜的活性

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.00588-22
Souche, Aubin; Kolenda, Camille; Teoli, Jordan; Schuch, Raymond; Ferry, Tristan; Laurent, Frédéric; Josse, Jérôme
炎症/感染
微生物学
发表日期：2022
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Direct Lytic Agents: Novel, Rapidly Acting Potential Antimicrobial Treatment Modalities for Systemic Use in the Era of Rising Antibiotic Resistance

直接溶菌剂：在抗生素耐药性日益严重的时代，新型、快速起效的潜在全身性抗菌治疗手段

期刊:Frontiers in Microbiology
影响因子:4.5
doi:10.3389/fmicb.2022.841905
Schuch, Raymond; Cassino, Cara; Vila-Farres, Xavier
发表日期：2022
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Locally delivered antistaphylococcal lysin exebacase or CF-296 is active in methicillin-resistant Staphylococcus aureus implant-associated osteomyelitis

局部应用抗葡萄球菌溶菌酶 exebacase 或 CF-296 对耐甲氧西林金黄色葡萄球菌植入物相关性骨髓炎有效。

期刊:Journal of Bone and Joint Infection
影响因子:2.8
doi:10.5194/jbji-7-169-2022
Karau, Melissa; Schmidt-Malan, Suzannah; Mandrekar, Jay; Lehoux, Dario; Schuch, Raymond; Cassino, Cara; Patel, Robin
骨髓炎
发表日期：2022
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Determination of MIC Quality Control Parameters for Exebacase, a Novel Lysin with Antistaphylococcal Activity

测定新型抗葡萄球菌活性溶菌酶Exebacase的最小抑菌浓度(MIC)质量控制参数

期刊:Journal of Clinical Microbiology
影响因子:5.4
doi:10.1128/JCM.03117-20
Traczewski, Maria M; Ambler, Jane E; Schuch, Raymond
发表日期：2021
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Correction for Oh et al., "Development of a Broth Microdilution Method for Exebacase Susceptibility Testing"

对 Oh 等人的论文“用于 Exebacase 敏感性测试的肉汤微量稀释法的开发”的更正

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.01658-21
Oh, Jun T; Ambler, Jane E; Cassino, Cara; Schuch, Raymond
发表日期：2021
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Activity of Lysin CF-296 Alone and in Addition to Daptomycin in a Rat Model of Experimental Methicillin-Resistant Staphylococcus aureus Osteomyelitis

赖氨酸CF-296单独使用及与达托霉素联用在实验性耐甲氧西林金黄色葡萄球菌骨髓炎大鼠模型中的活性

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00117-21
Karau, Melissa J; Schmidt-Malan, Suzannah M; Mandrekar, Jay; Lehoux, Dario; Schuch, Raymond; Cassino, Cara; Patel, Robin
Rat
骨髓炎
发表日期：2021
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