Deficiencies in the Fanconi anemia or homologous recombination pathway enhance the antitumor effects of the hypoxia-activated prodrug CP-506
范可尼贫血或同源重组途径的缺陷会增强缺氧激活前药CP-506的抗肿瘤作用。
期刊:Molecular Therapy Oncology
影响因子:5.3
doi:10.1016/j.omton.2026.201161
Schuitmaker, Lesley; van der Wiel, Alexander M A; Lieuwes, Natasja G; Biemans, Rianne; Mutsters, Nikki A M; Jung, Jennifer; Bastos, Victoria Claudino; Sagarra, Èlia Prades; Kuang, Sheng; Setton, Jeremy; Langie, Sabine A S; Kampen, Kim R; Theys, Jan; Yaromina, Ala; Dubois, Ludwig J; Lambin, Philippe