日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeted serum proteomics of longitudinal samples from newly diagnosed youth with type 1 diabetes distinguishes markers of disease and C-peptide trajectory

对新诊断的1型糖尿病青少年纵向样本进行靶向血清蛋白质组学分析,可区分疾病标志物和C肽轨迹

Moulder, Robert; Välikangas, Tommi; Hirvonen, M Karoliina; Suomi, Tomi; Brorsson, Caroline A; Lietzén, Niina; Bruggraber, Sylvaine F A; Overbergh, Lut; Dunger, David B; Peakman, Mark; Chmura, Piotr J; Brunak, Soren; Schulte, Anke M; Mathieu, Chantal; Knip, Mikael; Elo, Laura L; Lahesmaa, Riitta

INNODIA Master Protocol for the evaluation of investigational medicinal products in children, adolescents and adults with newly diagnosed type 1 diabetes

INNODIA 主方案用于评估在新诊断为 1 型糖尿病的儿童、青少年和成人中的研究性药物

Dunger, David B; Bruggraber, Sylvaine F A; Mander, Adrian P; Marcovecchio, M Loredana; Tree, Timothy; Chmura, Piotr Jaroslaw; Knip, Mikael; Schulte, Anke M; Mathieu, Chantal

Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion

对STARD10基因座的染色质三维相互作用分析揭示了FCHSD2是胰岛素分泌的调节因子

Hu, Ming; Cebola, Inês; Carrat, Gaelle; Jiang, Shuying; Nawaz, Sameena; Khamis, Amna; Canouil, Mickaël; Froguel, Philippe; Schulte, Anke; Solimena, Michele; Ibberson, Mark; Marchetti, Piero; Cardenas-Diaz, Fabian L; Gadue, Paul J; Hastoy, Benoit; Almeida-Souza, Leonardo; McMahon, Harvey; Rutter, Guy A

Study protocol: Minimum effective low dose: anti-human thymocyte globulin (MELD-ATG): phase II, dose ranging, efficacy study of antithymocyte globulin (ATG) within 6 weeks of diagnosis of type 1 diabetes

研究方案:最低有效低剂量:抗人胸腺细胞球蛋白(MELD-ATG):II期剂量范围研究,评估抗胸腺细胞球蛋白(ATG)在1型糖尿病确诊后6周内的疗效

Wilhelm-Benartzi, Charlotte S; Miller, Sarah E; Bruggraber, Sylvaine; Picton, Diane; Wilson, Mark; Gatley, Katrina; Chhabra, Anita; Marcovecchio, M Loredana; Hendriks, A Emile J; Morobé, Hilde; Chmura, Piotr Jaroslaw; Bond, Simon; Aschemeier-Fuchs, Bärbel; Knip, Mikael; Tree, Timothy; Overbergh, Lut; Pall, Jaivier; Arnaud, Olivier; Haller, Michael J; Nitsche, Almut; Schulte, Anke M; Mathieu, Chantal; Mander, Adrian; Dunger, David

Fostering improved human islet research: a European perspective

促进人类胰岛研究的进步:欧洲视角

Marchetti, Piero; Schulte, Anke M; Marselli, Lorella; Schoniger, Eyke; Bugliani, Marco; Kramer, Werner; Overbergh, Lut; Ullrich, Susanne; Gloyn, Anna L; Ibberson, Mark; Rutter, Guy; Froguel, Philippe; Groop, Leif; McCarthy, Mark I; Dotta, Francesco; Scharfmann, Raphael; Magnan, Christophe; Eizirik, Decio L; Mathieu, Chantal; Cnop, Miriam; Thorens, Bernard; Solimena, Michele

Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2 diabetes

利用激光捕获显微切割技术对人胰岛进行分析,揭示了与2型糖尿病相关的新型eQTL。

Khamis, Amna; Canouil, Mickaël; Siddiq, Afshan; Crouch, Hutokshi; Falchi, Mario; Bulow, Manon von; Ehehalt, Florian; Marselli, Lorella; Distler, Marius; Richter, Daniela; Weitz, Jürgen; Bokvist, Krister; Xenarios, Ioannis; Thorens, Bernard; Schulte, Anke M; Ibberson, Mark; Bonnefond, Amelie; Marchetti, Piero; Solimena, Michele; Froguel, Philippe

Metabolically phenotyped pancreatectomized patients as living donors for the study of islets in health and diabetes

对接受胰腺切除术的患者进行代谢表型分析,并将他们作为活体供体用于健康和糖尿病状态下胰岛的研究。

Barovic, Marko; Distler, Marius; Schöniger, Eyke; Radisch, Nicole; Aust, Daniela; Weitz, Jürgen; Ibberson, Mark; Schulte, Anke M; Solimena, Michele

Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes

IMIDIA生物样本库的系统生物学研究(样本来自器官捐献者和胰腺切除患者)揭示了2型糖尿病患者胰岛的新型转录组特征。

Solimena, Michele; Schulte, Anke M; Marselli, Lorella; Ehehalt, Florian; Richter, Daniela; Kleeberg, Manuela; Mziaut, Hassan; Knoch, Klaus-Peter; Parnis, Julia; Bugliani, Marco; Siddiq, Afshan; Jörns, Anne; Burdet, Frédéric; Liechti, Robin; Suleiman, Mara; Margerie, Daniel; Syed, Farooq; Distler, Marius; Grützmann, Robert; Petretto, Enrico; Moreno-Moral, Aida; Wegbrod, Carolin; Sönmez, Anke; Pfriem, Katja; Friedrich, Anne; Meinel, Jörn; Wollheim, Claes B; Baretton, Gustavo B; Scharfmann, Raphael; Nogoceke, Everson; Bonifacio, Ezio; Sturm, Dorothée; Meyer-Puttlitz, Birgit; Boggi, Ugo; Saeger, Hans-Detlev; Filipponi, Franco; Lesche, Mathias; Meda, Paolo; Dahl, Andreas; Wigger, Leonore; Xenarios, Ioannis; Falchi, Mario; Thorens, Bernard; Weitz, Jürgen; Bokvist, Krister; Lenzen, Sigurd; Rutter, Guy A; Froguel, Philippe; von Bülow, Manon; Ibberson, Mark; Marchetti, Piero

Decreased STARD10 Expression Is Associated with Defective Insulin Secretion in Humans and Mice

STARD10表达降低与人类和小鼠胰岛素分泌缺陷相关

Carrat, Gaelle R; Hu, Ming; Nguyen-Tu, Marie-Sophie; Chabosseau, Pauline; Gaulton, Kyle J; van de Bunt, Martijn; Siddiq, Afshan; Falchi, Mario; Thurner, Matthias; Canouil, Mickaël; Pattou, Francois; Leclerc, Isabelle; Pullen, Timothy J; Cane, Matthew C; Prabhala, Priyanka; Greenwald, William; Schulte, Anke; Marchetti, Piero; Ibberson, Mark; MacDonald, Patrick E; Manning Fox, Jocelyn E; Gloyn, Anna L; Froguel, Philippe; Solimena, Michele; McCarthy, Mark I; Rutter, Guy A

Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion.

葡萄糖调节和药物扰动的磷酸化蛋白质组揭示了控制胰岛素分泌的分子机制

Sacco Francesca, Humphrey Sean J, Cox Jürgen, Mischnik Marcel, Schulte Anke, Klabunde Thomas, Schäfer Matthias, Mann Matthias