Schulte Uwe相关文献与解析，生知库 | 链接生命科学的每一步

Vinayagam, Deivanayagabarathy; Sitsel, Oleg; Schulte, Uwe; Constantin, Cristina E; Oosterheert, Wout; Prumbaum, Daniel; Zolles, Gerd; Fakler, Bernd; Raunser, Stefan

发表日期：2025

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Mitochondrial KMT9 methylates DLAT to control pyruvate dehydrogenase activity and prostate cancer growth

线粒体KMT9通过甲基化DLAT来控制丙酮酸脱氢酶活性和前列腺癌生长。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-56492-8

Jia, Yanhan; Wang, Sheng; Urban, Sylvia; Müller, Judith M; Sum, Manuela; Wang, Qing; Bauer, Helena; Schulte, Uwe; Rampelt, Heike; Pfanner, Nikolaus; Schüle, Katrin M; Imhof, Axel; Forné, Ignasi; Berlin, Christopher; Sigle, August; Gratzke, Christian; Greschik, Holger; Metzger, Eric; Schüle, Roland

Ca(2+)-pumping by PMCA-neuroplastin complexes operates in the kiloHertz-range.

PMCA-神经塑性蛋白复合物的 Ca(2+) 泵送作用在千赫兹范围内进行

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-62735-5

Constantin Cristina E, Schmidt Barbara, Schwarz Yvonne, Harada Harumi, Kollewe Astrid, MÃ¼ller Catrin S, Henrich Sebastian, Gaal Botond, Kulik Akos, Bruns Dieter, Schulte Uwe, Rieger Heiko, Fakler Bernd

神经科学

发表日期：2025

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Endosomal chloride/proton exchangers need inhibitory TMEM9 Î²-subunits for regulation and prevention of disease-causing overactivity.

内体氯离子/质子交换器需要抑制性TMEM9β亚基来调节和预防致病性过度活跃

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-58546-3

Planells-Cases Rosa, Vorobeva Viktoriia, Kar Sumanta, Schmitt Franziska W, Schulte Uwe, Schrecker Marina, Hite Richard K, Fakler Bernd, Jentsch Thomas J

其它

发表日期：2025

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Structural basis of ClC-3 inhibition by TMEM9 and PI(3,5)P(2).

TMEM9 和 PI(3,5)P(2) 抑制 ClC-3 的结构基础

期刊:

影响因子:

doi:10.1101/2025.02.28.640562

Schrecker Marina, Son Yeeun, Planells-Cases Rosa, Kar Sumanta, Vorobeva Viktoriia, Schulte Uwe, Fakler Bernd, Jentsch Thomas J, Hite Richard K

信号转导

发表日期：2025

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Identification of MIMAS, a multifunctional mega-assembly integrating metabolic and respiratory biogenesis factors of mitochondria.

MIMAS 的鉴定，MIMAS 是一种多功能巨型组装体，整合了线粒体的代谢和呼吸生物合成因子

期刊:Cell Reports

影响因子:6.9

doi:10.1016/j.celrep.2024.113772

Horten Patrick, Song Kuo, Garlich Joshua, Hardt Robert, Colina-Tenorio Lilia, Horvath Susanne E, Schulte Uwe, Fakler Bernd, van der Laan Martin, Becker Thomas, Stuart Rosemary A, Pfanner Nikolaus, Rampelt Heike

Mitochondrial complexome reveals quality-control pathways of protein import

线粒体复合物组揭示蛋白质输入的质量控制通路

期刊:Nature

影响因子:48.5

doi:10.1038/s41586-022-05641-w

Schulte, Uwe; den Brave, Fabian; Haupt, Alexander; Gupta, Arushi; Song, Jiyao; Müller, Catrin S; Engelke, Jeannine; Mishra, Swadha; Mårtensson, Christoph; Ellenrieder, Lars; Priesnitz, Chantal; Straub, Sebastian P; Doan, Kim Nguyen; Kulawiak, Bogusz; Bildl, Wolfgang; Rampelt, Heike; Wiedemann, Nils; Pfanner, Nikolaus; Fakler, Bernd; Becker, Thomas

Flavonol-mediated stabilization of PIN efflux complexes regulates polar auxin transport

黄酮醇介导的PIN外排复合物稳定作用调控极性生长素运输

期刊:EMBO Journal

影响因子:8.3

doi:10.15252/embj.2020104416

Teale, William D; Pasternak, Taras; Dal Bosco, Cristina; Dovzhenko, Alexander; Kratzat, Krystyna; Bildl, Wolfgang; Schwörer, Manuel; Falk, Thorsten; Ruperti, Benadetto; Schaefer, Jonas V; Shahriari, Mojgan; Pilgermayer, Lena; Li, Xugang; Lübben, Florian; Plückthun, Andreas; Schulte, Uwe; Palme, Klaus

信号转导

发表日期：2021

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N-Myc-induced metabolic rewiring creates novel therapeutic vulnerabilities in neuroblastoma

N-Myc诱导的代谢重组为神经母细胞瘤的治疗带来了新的弱点

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-020-64040-1

Britta Tjaden #, Katharina Baum #, Viktoria Marquardt, Mareike Simon, Marija Trajkovic-Arsic, Theresa Kouril, Bettina Siebers, Jan Lisec, Jens T Siveke, Johannes H Schulte, Uwe Benary, Marc Remke, Jana Wolf, Alexander Schramm

GlialCAM, a protein defective in a leukodystrophy, serves as a ClC-2 Cl(-) channel auxiliary subunit

胶质细胞黏附分子（GlialCAM）是一种在脑白质营养不良症中存在缺陷的蛋白质，它作为ClC-2氯离子通道的辅助亚基发挥作用。

期刊:Neuron

影响因子:15

doi:10.1016/j.neuron.2011.12.039

Jeworutzki, Elena; López-Hernández, Tania; Capdevila-Nortes, Xavier; Sirisi, Sònia; Bengtsson, Luiza; Montolio, Marisol; Zifarelli, Giovanni; Arnedo, Tanit; Müller, Catrin S; Schulte, Uwe; Nunes, Virginia; Martínez, Albert; Jentsch, Thomas J; Gasull, Xavier; Pusch, Michael; Estévez, Raúl

Molecular mechanism of ultrafast transport by plasma membrane Ca(2+)-ATPases

质膜Ca(2+)-ATP酶介导的超快转运的分子机制

Mitochondrial KMT9 methylates DLAT to control pyruvate dehydrogenase activity and prostate cancer growth

线粒体KMT9通过甲基化DLAT来控制丙酮酸脱氢酶活性和前列腺癌生长。

Ca(2+)-pumping by PMCA-neuroplastin complexes operates in the kiloHertz-range.

PMCA-神经塑性蛋白复合物的 Ca(2+) 泵送作用在千赫兹范围内进行

Endosomal chloride/proton exchangers need inhibitory TMEM9 Î²-subunits for regulation and prevention of disease-causing overactivity.

内体氯离子/质子交换器需要抑制性TMEM9β亚基来调节和预防致病性过度活跃

Structural basis of ClC-3 inhibition by TMEM9 and PI(3,5)P(2).

TMEM9 和 PI(3,5)P(2) 抑制 ClC-3 的结构基础

Identification of MIMAS, a multifunctional mega-assembly integrating metabolic and respiratory biogenesis factors of mitochondria.

MIMAS 的鉴定，MIMAS 是一种多功能巨型组装体，整合了线粒体的代谢和呼吸生物合成因子

Mitochondrial complexome reveals quality-control pathways of protein import

线粒体复合物组揭示蛋白质输入的质量控制通路

Flavonol-mediated stabilization of PIN efflux complexes regulates polar auxin transport

黄酮醇介导的PIN外排复合物稳定作用调控极性生长素运输

N-Myc-induced metabolic rewiring creates novel therapeutic vulnerabilities in neuroblastoma

N-Myc诱导的代谢重组为神经母细胞瘤的治疗带来了新的弱点

GlialCAM, a protein defective in a leukodystrophy, serves as a ClC-2 Cl(-) channel auxiliary subunit

胶质细胞黏附分子（GlialCAM）是一种在脑白质营养不良症中存在缺陷的蛋白质，它作为ClC-2氯离子通道的辅助亚基发挥作用。