文献库，生知库 | 链接生命科学的每一步

日期影响因子

Epigenetic priming of neural progenitors by Notch enhances Sonic hedgehog signaling and establishes gliogenic competence

Notch通过表观遗传调控神经祖细胞，增强Sonic hedgehog信号通路，并建立胶质细胞生成能力。

期刊:Genes & Development

影响因子:7.7

doi:10.1101/gad.352555.124

Tran, Luuli N; Shinde, Ashwini; Schuster, Kristen H; Sabaawy, Aiman; Dale, Emily; Welch, Madalynn J; Isner, Trevor J; Nunez, Sylvia A; García-Moreno, Fernando; Sagerström, Charles G; Appel, Bruce H; Franco, Santos J

细胞生物学

发表日期：2025

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ASOs are an effective treatment for disease-associated oligodendrocyte signatures in premanifest and symptomatic SCA3 mice.

ASO 可有效治疗 SCA3 前驱期和症状期小鼠的疾病相关少突胶质细胞特征

期刊:Molecular Therapy

影响因子:12

doi:10.1016/j.ymthe.2024.02.033

Schuster Kristen H, Zalon Annie J, DiFranco Danielle M, Putka Alexandra F, Stec Nicholas R, Jarrah Sabrina I, Naeem Arsal, Haque Zaid, Zhang Hanrui, Guan Yuanfang, McLoughlin Hayley S

细胞生物学

发表日期：2024

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Antisense Oligonucleotide Silencing Reverses Abnormal Neurochemistry in Spinocerebellar Ataxia 3 Mice

反义寡核苷酸沉默逆转脊髓小脑性共济失调3型小鼠的异常神经化学

期刊:Annals of Neurology

影响因子:7.7

doi:10.1002/ana.26713

McLoughlin, Hayley S; Gundry, Katherine; Rainwater, Orion; Schuster, Kristen H; Wellik, Isabel G; Zalon, Annie J; Benneyworth, Michael A; Eberly, Lynn E; Öz, Gülin

发表日期：2023

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Blood levels of neurofilament light are associated with disease progression in a mouse model of spinocerebellar ataxia type 3

在脊髓小脑性共济失调3型小鼠模型中，神经丝轻链的血液水平与疾病进展相关

期刊:Disease Models & Mechanisms

影响因子:3.3

doi:10.1242/dmm.050144

Mengel, David; Wellik, Isabel G; Schuster, Kristen H; Jarrah, Sabrina I; Wacker, Madeleine; Ashraf, Naila S; Öz, Gülin; Synofzik, Matthis; Costa, Maria do Carmo; McLoughlin, Hayley S

发表日期：2023

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Blood neurofilament light chain levels are associated with disease progression in a transgenic SCA3 mouse model

在转基因SCA3小鼠模型中，血液神经丝轻链水平与疾病进展相关。

doi:10.1101/2023.02.28.530463

Mengel, David; Wellik, Isabel G; Schuster, Kristen H; Jarrah, Sabrina I; Wacker, Madeleine; Ashraf, Naila S; Öz, Gülin; Synofzik, Matthis; do Carmo Costa, Maria; McLoughlin, Hayley S

发表日期：2023

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Pathogenetic Mechanisms Underlying Spinocerebellar Ataxia Type 3 Are Altered in Primary Oligodendrocyte Culture.

原代少突胶质细胞培养改变了脊髓小脑性共济失调3型的发病机制

影响因子:5.2

doi:10.3390/cells11162615

Schuster Kristen H, Putka Alexandra F, McLoughlin Hayley S

细胞生物学

发表日期：2022

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