日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genomic landscape and clonal architecture in pediatric myeloid neoplasms with chromosome 7 deletions

染色体 7 缺失的儿童髓系肿瘤的基因组图谱和克隆结构

Westover, Tamara; Walsh, Michael P; Abdelhamed, Sherif; Xiong, Emily; Ma, Jing; Song, Guangchun; Thomas, Melvin E 3rd; Umeda, Masayuki; Maciaszek, Jamie L; Wong, Jasmine C; Wintering, Astrid; Wang, Lu; Emanuel, Peter D; Loh, Mignon L; Tasian, Sarah K; Stieglitz, Elliot; Schwartz, Jason R; Shannon, Kevin M; Klco, Jeffery M

Overexpression of human SAMD9 inhibits protein translation and alters MYC signaling resulting in cell cycle arrest.

人类 SAMD9 的过度表达会抑制蛋白质翻译并改变 MYC 信号传导,从而导致细胞周期停滞

McSweeney Kristen, Hoover Paul, Ramirez-Solano Marisol, Liu Qi, Schwartz Jason R

The acquisition of molecular drivers in pediatric therapy-related myeloid neoplasms

儿童治疗相关髓系肿瘤中分子驱动因素的获得

Schwartz, Jason R; Ma, Jing; Kamens, Jennifer; Westover, Tamara; Walsh, Michael P; Brady, Samuel W; Robert Michael, J; Chen, Xiaolong; Montefiori, Lindsey; Song, Guangchun; Wu, Gang; Wu, Huiyun; Branstetter, Cristyn; Hiltenbrand, Ryan; Walsh, Michael F; Nichols, Kim E; Maciaszek, Jamie L; Liu, Yanling; Kumar, Priyadarshini; Easton, John; Newman, Scott; Rubnitz, Jeffrey E; Mullighan, Charles G; Pounds, Stanley; Zhang, Jinghui; Gruber, Tanja; Ma, Xiaotu; Klco, Jeffery M

Donor-derived MDS/AML in families with germline GATA2 mutation

携带种系 GATA2 突变的家族中供者来源的 MDS/AML

Galera, Pallavi; Hsu, Amy P; Wang, Weixin; Droll, Stephenie; Chen, Rui; Schwartz, Jason R; Klco, Jeffery M; Arai, Sally; Maese, Luke; Zerbe, Christa; Parta, Mark J; Young, Neal S; Holland, Steven M; Hickstein, Dennis D; Calvo, Katherine R

Clonal dynamics of donor-derived myelodysplastic syndrome after unrelated hematopoietic cell transplantation for high-risk pediatric B-lymphoblastic leukemia

高危儿童B淋巴母细胞白血病无关供者造血干细胞移植后供者来源骨髓增生异常综合征的克隆动力学

Schwartz, Jason R; Walsh, Michael P; Ma, Jing; Lamprecht, Tamara; Wang, Shuoguo; Wu, Gang; Raimondi, Susana; Triplett, Brandon M; Klco, Jeffery M

Epigenetic alteration by DNA-demethylating treatment restores apoptotic response to glucocorticoids in dexamethasone-resistant human malignant lymphoid cells

DNA去甲基化治疗引起的表观遗传改变可恢复地塞米松耐药的人类恶性淋巴细胞对糖皮质激素的凋亡反应。

Miller, Aaron L; Geng, Chuandong; Golovko, Georgiy; Sharma, Meenakshi; Schwartz, Jason R; Yan, Jiabin; Sowers, Lawrence; Widger, William R; Fofanov, Yuriy; Vedeckis, Wayne V; Thompson, E Brad

c-Myb interacts with the glucocorticoid receptor and regulates its level in pre-B-acute lymphoblastic leukemia cells.

c-Myb 与糖皮质激素受体相互作用,并调节前 B 细胞急性淋巴细胞白血病细胞中糖皮质激素受体的水平

Sarvaiya Purvaba J, Schwartz Jason R, Geng Chuan-dong, Vedeckis Wayne V

A facile, branched DNA assay to quantitatively measure glucocorticoid receptor auto-regulation in T-cell acute lymphoblastic leukemia

一种简便的、分支状的DNA检测方法,用于定量测量T细胞急性淋巴细胞白血病中糖皮质激素受体的自身调节。

Schwartz, Jason R; Sarvaiya, Purvaba J; Leiva, Lily E; Velez, Maria C; Singleton, Tammuella C; Yu, Lolie C; Vedeckis, Wayne V

Glucocorticoid receptor knock down reveals a similar apoptotic threshold but differing gene regulation patterns in T-cell and pre-B-cell acute lymphoblastic leukemia

糖皮质激素受体敲低揭示了T细胞和前B细胞急性淋巴细胞白血病中相似的凋亡阈值,但基因调控模式不同。

Schwartz, Jason R; Sarvaiya, Purvaba J; Vedeckis, Wayne V