日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Systemic immunostimulation induces glucocorticoid-mediated thymic involution succeeded by rebound hyperplasia which is impaired in aged recipients

全身免疫刺激诱导糖皮质激素介导的胸腺退化,随后发生反弹性增生,而老年接受者则受损

Craig P Collins, Lam T Khuat, Gail D Sckisel, Logan V Vick, Christine M Minnar, Cordelia Dunai, Catherine T Le, Brendan D Curti, Marka Crittenden, Alexander Merleev, Michael Sheng, Nelson J Chao, Emanual Maverakis, Spencer R Rosario, Arta M Monjazeb, Bruce R Blazar, Dan L Longo, Robert J Canter, Wil

Engineered IL-21 Cytokine Muteins Fused to Anti-PD-1 Antibodies Can Improve CD8+ T Cell Function and Anti-tumor Immunity

与抗 PD-1 抗体融合的工程化 IL-21 细胞因子突变蛋白可改善 CD8+ T 细胞功能和抗肿瘤免疫力

Shanling Shen, Gail Sckisel, Anupama Sahoo, Almin Lalani, Doug Den Otter, Josh Pearson, Jason DeVoss, Jay Cheng, Stephanie C Casey, Ryan Case, Melissa Yang, Ray Low, Mark Daris, Bin Fan, Neeraj J Agrawal, Khaled Ali

Differential phenotypes of memory CD4 and CD8 T cells in the spleen and peripheral tissues following immunostimulatory therapy

免疫刺激治疗后脾脏和外周组织中记忆性 CD4 和 CD8 T 细胞的差异表型

Gail D Sckisel, Annie Mirsoian, Christine M Minnar, Marka Crittenden, Brendan Curti, Jane Q Chen, Bruce R Blazar, Alexander D Borowsky, Arta M Monjazeb, William J Murphy

Blocking Indolamine-2,3-Dioxygenase Rebound Immune Suppression Boosts Antitumor Effects of Radio-Immunotherapy in Murine Models and Spontaneous Canine Malignancies

阻断吲哚胺-2,3-双加氧酶反弹免疫抑制可增强放射免疫疗法在小鼠模型和自发性犬恶性肿瘤中的抗肿瘤作用

Monjazeb, Arta M; Kent, Michael S; Grossenbacher, Steven K; Mall, Christine; Zamora, Anthony E; Mirsoian, Annie; Chen, Mingyi; Kol, Amir; Shiao, Stephen L; Reddy, Abhinav; Perks, Julian R; T N Culp, William; Sparger, Ellen E; Canter, Robert J; Sckisel, Gail D; Murphy, William J

Repeated PD-1/PD-L1 monoclonal antibody administration induces fatal xenogeneic hypersensitivity reactions in a murine model of breast cancer

在乳腺癌小鼠模型中,重复注射PD-1/PD-L1单克隆抗体可诱发致命的异种超敏反应。

Mall, Christine; Sckisel, Gail D; Proia, David A; Mirsoian, Annie; Grossenbacher, Steven K; Pai, Chien-Chun Steven; Chen, Mingyi; Monjazeb, Arta M; Kelly, Karen; Blazar, Bruce R; Murphy, William J

Out-of-Sequence Signal 3 Paralyzes Primary CD4(+) T-Cell-Dependent Immunity

序列错误信号3会麻痹原发性CD4(+) T细胞依赖性免疫

Sckisel, Gail D; Bouchlaka, Myriam N; Monjazeb, Arta M; Crittenden, Marka; Curti, Brendan D; Wilkins, Danice E C; Alderson, Kory A; Sungur, Can M; Ames, Erik; Mirsoian, Annie; Reddy, Abhinav; Alexander, Warren; Soulika, Athena; Blazar, Bruce R; Longo, Dan L; Wiltrout, Robert H; Murphy, William J

NK Cells Preferentially Target Tumor Cells with a Cancer Stem Cell Phenotype

NK 细胞优先攻击具有癌症干细胞表型的肿瘤细胞

Erik Ames, Robert J Canter, Steven K Grossenbacher, Stephanie Mac, Mingyi Chen, Rachel C Smith, Takeshi Hagino, Jessica Perez-Cunningham, Gail D Sckisel, Shiro Urayama, Arta M Monjazeb, Ruben C Fragoso, Thomas J Sayers, William J Murphy

Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice

老年小鼠接受系统性刺激性免疫治疗方案后,肥胖会诱发致命的细胞因子风暴

Annie Mirsoian, Myriam N Bouchlaka, Gail D Sckisel, Mingyi Chen, Chien-Chun Steven Pai, Emanuel Maverakis, Richard G Spencer, Kenneth W Fishbein, Sana Siddiqui, Arta M Monjazeb, Bronwen Martin, Stuart Maudsley, Charles Hesdorffer, Luigi Ferrucci, Dan L Longo, Bruce R Blazar, Robert H Wiltrout, Denni

Increased antitumor effects using IL-2 with anti-TGF-β reveals competition between mouse NK and CD8 T cells

IL-2 与抗 TGF-β 联合使用可增强抗肿瘤作用,揭示小鼠 NK 细胞和 CD8 T 细胞之间的竞争

Maite Alvarez, Myriam N Bouchlaka, Gail D Sckisel, Can M Sungur, Mingyi Chen, William J Murphy

Influenza infection results in local expansion of memory CD8(+) T cells with antigen non-specific phenotype and function

流感感染导致具有抗原非特异性表型和功能的记忆性 CD8(+) T 细胞局部扩增

Gail D Sckisel, Julia K Tietze, Anthony E Zamora, Hua-Hui Hsiao, Stephen O Priest, Danice E C Wilkins, Louis L Lanier, Bruce R Blazar, Nicole Baumgarth, William J Murphy