日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Investigation of Profile-Related Evidence Determining Individualized Cancer Therapy (I-PREDICT) N-of-1 Precision Oncology Study: Molecular Profiling to Match Individually Dosed, Personalized Drug Combinations

基于分子谱分析确定个体化癌症治疗的证据调查(I-PREDICT)N-of-1精准肿瘤学研究:分子谱分析匹配个体化给药的个性化药物组合

Sicklick, Jason K; Nishizaki, Daisuke; Miyashita, Hirotaka; Okamura, Ryosuke; Hahn, Michael E; Nikanjam, Mina; Fanta, Paul T; Piccioni, David E; Patel, Hitendra; Eskander, Ramez N; McKay, Rana R; Ross, Jeffrey S; Lee, J Jack; Lippman, Scott M; Kato, Shumei; Kurzrock, Razelle

Genomic and transcriptomic analyses of aortic stenosis enhance therapeutic target discovery and disease prediction.

主动脉狭窄的基因组学和转录组学分析有助于发现治疗靶点和预测疾病。

Small Aeron M, Yang Ta-Yu, Itoh Shinsuke, Thériault Sébastien, Dufresne Line, Kurosawa Ryo, Komuro Issei, Matsuda Koichi, Vy Ha My T, Farber-Eger Eric H, Shaffer Lauren Lee, Boulier Kristin M, Corey Kristin M, Ramaker Megan E, Laporte Fabien, Schott Jean-Jacques, Le Scouarnec Solena, Singh Sasha A, Sonawane Abhijeet R, Smith Harry A, Rafaels Nicholas, Ghouse Jonas, Raja Anna A, Ostrowski Sisse R, Sørensen Erik, Mikkelsen Christina, Pedersen Ole B, Erikstrup Christian, Ullum Henrik, Sveinbjornsson Gardar, Gudbjartsson Daniel F, Abner Erik, Lee Jiwoo, Ganna Andrea, Nowak-Göttl Ulrike, Finer Sarah, Schumacher Johannes, Maj Carlo, Al-Kassou Baravan, Nickenig Georg, Trenkwalder Teresa, Dreβen Martina, Krane Markus, Nöthen Markus M, Moksnes Marta R, Brumpton Ben M, Knight Stacey, Knowlton Kirk U, Nadauld Lincoln, Debiec Radek, Musameh Muntaser D, Braund Peter S, Nelson Christopher P, Czuba Tomasz, Melander Olle, Selvaraj Margaret Sunitha, Koyama Satoshi, Bhukar Rohan, Ruan Yunfeng, Ljungberg Johan, Damrauer Scott M, Levin Michael G, Franke Andre, Berger Klaus, Ruff Christian T, Melloni Giorgio E M, Kamanu Frederick K, Ito Kaoru, Do Ron, Loos Ruth J F, Schunkert Heribert, Wells Quinn S, Shah Svati H, Le Tourneau Thierry, Messika-Zeitoun David, Gignoux Christopher, Bundgaard Henning, Larsson Susanna C, Michaëlsson Karl, Holm Hilma, Helgadottir Anna, Esko Tonu, van Heel David A, Mathieu Patrick, Samani Nilesh J, Smith J Gustav, Söderberg Stefan, Rader Daniel J, Marston Nicholas A, Sabatine Marc S, Pasaniuc Bogdan, Cho Kelly, Wilson Peter W F, O'Donnell Christopher J, Stefansson Kari, Bossé Yohan, Aikawa Elena, Engert James C, Peloso Gina M, Natarajan Pradeep, Thanassoulis George

Clinical Features Associated with Chronic Lung Allograft Dysfunction Progression in a Multicenter Cohort

多中心队列研究中与慢性肺移植功能障碍进展相关的临床特征

Todd, Jamie L; Neely, Megan L; Hsu, Jesse Y; Diamond, Joshua M; Anderson, Michaela R; Cantu, Edward; Clausen, Emily; Pandya, Krishna; Oyster, Michelle; Kalman, Laurel; Frankel, Courtney W; Benvenuto, Luke; Combs, Michael; Dhillon, Gundeep; McDyer, John; Patel, Mrunal; Shah, Pali D; Singer, Jonathan P; Snyder, Laurie D; Christie, Jason D; Palmer, Scott M

Shared Genetic Liability across Systems of Psychiatric and Physical Illness

精神疾病和躯体疾病系统中的共同遗传易感性

Lawrence, Jeremy M; Foote, Isabelle F; Breunig, Sophie; Schaffer, Lukas S; Lyons, Siraj; Abramowitz, Sarah A; Levin, Michael G; Damrauer, Scott M; Mallard, Travis T; Grotzinger, Andrew D

Lyn governs the establishment and maintenance of B cell anergy by suppressing PI3K signaling

Lyn通过抑制PI3K信号传导来调控B细胞无反应性的建立和维持。

Fiske, Brigita E; Wemlinger, Scott M; Crute, Bergren W; Getahun, Andrew

Hepatic steatosis in humans is associated with preserved glucagon action on amino acid metabolism

人类肝脂肪变性与胰高血糖素对氨基酸代谢的作用保留有关

Christie, Hannah E; Mohan, Sneha; Egan, Aoife M; Boscolo, Federica; Dalla Man, Chiara; Thompson, Scott M; Jundt, Michael; Fleming, Chad J; Andrews, James C; Bailey, Kent R; Jensen, Michael D; Nair, K Sree; Vella, Adrian

Systemic Manifestations and Mortality Risk in Transthyretin V142I Variant Carriers: A Million Veteran Program Analysis

转甲状腺素蛋白V142I变异携带者的全身表现和死亡风险:百万退伍军人计划分析

Sideris, Konstantinos; Nelson, Tyler J; Brinker, Lina; Gao, Anthony; Tcheandjieu, Catherine; Kyriakopoulos, Christos P; Berlowitz, Dan; Hull, Leland; Ferraro, Jeffrey P; Agiri, Fatai Y; Pridgen, Kathryn M; Roblin, Steven; Joseph, Jacob; Damrauer, Scott M; Chang, Kyong-Mi; Teerlink, Craig C; Stehlik, Josef; Carter, Spencer; Lynch, Julie A

Impact of vector copy number on critical quality attributes of retrovirally engineered T cells

载体拷贝数对逆转录病毒工程化T细胞关键质量属性的影响

Norberg, Scott M; Gund, Rupali; Doubrovina, Ekaterina; Doran, Stacey L; Fuksenko, Tatyana; Liu, Hui; Ma, Jinxia; Franco, Zulmarie; Hinrichs, Christian S

Genetic correlation analysis of Alzheimer's disease and stroke implicates PHLPP1 as a shared locus in individuals of African ancestry

阿尔茨海默病和中风的遗传相关性分析表明,PHLPP1是非洲裔人群中共同的致病基因位点。

Ray, Nicholas R; Kurup, Jiji; Kumar, Ajneesh; Rajabli, Farid; Wang, Liyong; Xu, Wanying; Jin, Fulai; Yilmaz, Elanur; Kizil, Caghan; Bertholim-Nasciben, Luciana; Moura, Sofia; Ramirez, Aura M; Baiyewu, Olusegun; Griswold, Anthony J; Coker, Motunrayo; Scott, Kyle M; Akinwande, Kazeem; Adams, Larry D; Diala, Samuel; Whitehead, Patrice G; McCauley, Jacob L; Ogunronbi, Mayowa; Hamilton-Nelson, Kara L; Damasceno, Albertino; Zaman, Andrew F; Blanton, Susan H; Akpalu, Albert; Cuccaro, Michael L; Wahab, Kolawole; McInerney, Katalina F; Nuytemans, Karen; Obiako, Reginald; Mena, Pedro R; Okubadejo, Njideka; Martinez, Izri M; Zewde, Yared Z; Gugssa, Seid A; Sarfo, Fred S; Kalaria, Raj; Ndetei, David M; Williams, Scott M; Caban-Holt, Allison; Tosto, Giuseppe; Haines, Jonathan L; Akinyemi, Rufus O; Ogunniyi, Adesola; Byrd, Goldie S; Bush, William S; Kunkle, Brian W; Vance, Jeffery M; Pericak-Vance, Margaret A; Reitz, Christiane

Dissecting Alzheimer's disease heritability across populations

剖析阿尔茨海默病在不同人群中的遗传性

Liu, Shiying; Bush, William S; Kunkle, Brian W; Byrd, Goldie S; Reitz, Christiane; Tosto, Giuseppe; Rajabli, Farid; Caban-Holt, Allison M; Cuccaro, Michael; Starks, Takiyah; Adams, Larry D; Feliciano, Briseida E; Akinyemi, Rufus; Vance, Jeffery M; Pericak-Vance, Margaret; Haines, Jonathan L; Crawford, Dana C; Williams, Scott M