日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ezh2 Delays Activation of Differentiation Genes During Normal Cerebellar Granule Neuron Development and in Medulloblastoma.

Ezh2 延迟正常小脑颗粒神经元发育和髓母细胞瘤中分化基因的激活

Purzner James, Brown Alexander S, Purzner Teresa, Ellis Lauren, Broski Sara, Litzenburger Ulrike, Andrews Kaytlin, Sharma Aryaman, Wang Xin, Taylor Michael D, Cho Yoon-Jae, Fuller Margaret T, Scott Matthew P

Single-molecule imaging of Hedgehog pathway protein Smoothened in primary cilia reveals binding events regulated by Patched1

利用单分子成像技术对初级纤毛中的 Hedgehog 通路蛋白 Smoothened 进行成像,揭示了 Patched1 调控的结合事件。

Milenkovic, Ljiljana; Weiss, Lucien E; Yoon, Joshua; Roth, Theodore L; Su, YouRong S; Sahl, Steffen J; Scott, Matthew P; Moerner, W E

AMP-Activated Protein Kinase Directly Phosphorylates and Destabilizes Hedgehog Pathway Transcription Factor GLI1 in Medulloblastoma.

AMP激活蛋白激酶直接磷酸化并使髓母细胞瘤中的Hedgehog通路转录因子GLI1不稳定

Li Yen-Hsing, Luo Jia, Mosley Yung-Yi C, Hedrick Victoria E, Paul Lake N, Chang Julia, Zhang GuangJun, Wang Yu-Kuo, Banko Max R, Brunet Anne, Kuang Shihuan, Wu Jen-Leih, Chang Chun-Ju, Scott Matthew P, Yang Jer-Yen

Regulation of ribosome biogenesis by nucleostemin 3 promotes local and systemic growth in Drosophila.

核仁蛋白 3 对核糖体生物合成的调控促进果蝇的局部和全身生长

Hartl Tom A, Ni Julie, Cao Jian, Suyama Kaye L, Patchett Stephanie, Bussiere Cyril, Gui Dan Yi, Tang Sheng, Kaplan Daniel D, Fish Matthew, Johnson Arlen W, Scott Matthew P

Genetic dissection of a cell-autonomous neurodegenerative disorder: lessons learned from mouse models of Niemann-Pick disease type C

对一种细胞自主性神经退行性疾病进行遗传学解析:从尼曼-匹克病C型小鼠模型中汲取的经验教训

Lopez, Manuel E; Scott, Matthew P

Neuropilin-2 contributes to tumorigenicity in a mouse model of Hedgehog pathway medulloblastoma

神经纤毛蛋白-2在Hedgehog通路髓母细胞瘤小鼠模型中促进肿瘤发生

Hayden Gephart, Melanie G; Su, YouRong Sophie; Bandara, Samuel; Tsai, Feng-Chiao; Hong, Jennifer; Conley, Nicholas; Rayburn, Helen; Milenkovic, Ljiljana; Meyer, Tobias; Scott, Matthew P

The chromatin remodeling factor Chd1l is required in the preimplantation embryo

染色质重塑因子Chd1l是植入前胚胎所必需的。

Snider, Alyssa C; Leong, Denise; Wang, Q Tian; Wysocka, Joanna; Yao, Mylene W M; Scott, Matthew P

Complement is dispensable for neurodegeneration in Niemann-Pick disease type C

补体对于尼曼-匹克病C型的神经退行性变并非必需。

Lopez, Manuel E; Klein, Andres D; Scott, Matthew P

Microtubules enable the planar cell polarity of airway cilia

微管赋予气道纤毛平面细胞极性。

Vladar, Eszter K; Bayly, Roy D; Sangoram, Ashvin M; Scott, Matthew P; Axelrod, Jeffrey D

Neuronal and epithelial cell rescue resolves chronic systemic inflammation in the lipid storage disorder Niemann-Pick C

神经元和上皮细胞的拯救可缓解尼曼-匹克C型脂质贮积症的慢性全身性炎症。

Lopez, Manuel E; Klein, Andrés D; Hong, Jennifer; Dimbil, Ubah J; Scott, Matthew P