日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

β-Arrestin-biased proteinase-activated receptor-2 antagonist C781 limits allergen-induced airway hyperresponsiveness and inflammation

β-Arrestin 偏向蛋白酶激活受体 2 拮抗剂 C781 可限制过敏原诱发的气道高反应性和炎症

Hillary V Schiff, Candy M Rivas, William P Pederson, Estevan Sandoval, Samuel Gillman, Joy Prisco, Moeno Kume, Gregory Dussor, Josef Vagner, Julie G Ledford, Theodore J Price, Kathryn A DeFea, Scott Boitano

C781, a β-Arrestin Biased Antagonist at Protease-Activated Receptor-2 (PAR2), Displays in vivo Efficacy Against Protease-Induced Pain in Mice

C781 是一种针对蛋白酶激活受体 2 (PAR2) 的 β-Arrestin 拮抗剂,在小鼠体内显示出对抗蛋白酶诱发疼痛的功效

Moeno Kume, Ayesha Ahmad, Stephanie Shiers, Michael D Burton, Kathryn A DeFea, Josef Vagner, Gregory Dussor, Scott Boitano, Theodore J Price

Proteinase-activated receptor-2 antagonist C391 inhibits Alternaria-induced airway epithelial signalling and asthma indicators in acute exposure mouse models

蛋白酶激活受体 2 拮抗剂 C391 抑制急性暴露小鼠模型中链格孢菌诱发的气道上皮信号和哮喘指标

Candy M Rivas, Michael C Yee, Kenneth J Addison, Marissa Lovett, Kasturi Pal, Julie G Ledford, Gregory Dussor, Theodore J Price, Josef Vagner, Kathryn A DeFea, Scott Boitano

Alternaria alternata-induced airway epithelial signaling and inflammatory responses via protease-activated receptor-2 expression

链格孢菌通过蛋白酶激活受体-2 表达诱导呼吸道上皮信号传导和炎症反应

Candy M Rivas, Hillary V Schiff, Aubin Moutal, Rajesh Khanna, Pawel R Kiela, Gregory Dussor, Theodore J Price, Josef Vagner, Kathryn A DeFea, Scott Boitano

A Role for Protease Activated Receptor Type 3 (PAR3) in Nociception Demonstrated Through Development of a Novel Peptide Agonist

通过开发新型肽激动剂证明蛋白酶激活受体 3 型 (PAR3) 在伤害感受中的作用

Juliet Mwirigi, Moeno Kume, Shayne N Hassler, Ayesha Ahmad, Pradipta R Ray, Changyu Jiang, Alexander Chamessian, Nakleh Mseeh, Breya P Ludwig, Benjamin D Rivera, Marvin T Nieman, Thomas Van de Ven, Ru-Rong Ji, Gregory Dussor, Scott Boitano, Josef Vagner, Theodore J Price

Myeloid-associated differentiation marker is a novel SP-A-associated transmembrane protein whose expression on airway epithelial cells correlates with asthma severity

髓系相关分化标志物是一种新型的SP-A相关跨膜蛋白,其在气道上皮细胞上的表达与哮喘严重程度相关。

Alane Blythe C Dy ,Paul R Langlais ,Natalie K Barker ,Kenneth J Addison ,Sasipa Tanyaratsrisakul ,Scott Boitano ,Stephanie A Christenson ,Monica Kraft ,Deborah Meyers ,Eugene R Bleecker ,Xingnan Li ,Julie G Ledford

The cellular basis of protease-activated receptor 2-evoked mechanical and affective pain

蛋白酶激活受体 2 诱发机械和情感疼痛的细胞基础

Shayne N Hassler, Moeno Kume, Juliet M Mwirigi, Ayesha Ahmad, Stephanie Shiers, Andi Wangzhou, Pradipta R Ray, Serge N Belugin, Dhananjay K Naik, Michael D Burton, Josef Vagner, Scott Boitano, Armen N Akopian, Gregory Dussor, Theodore J Price

The lipidated connexin mimetic peptide SRPTEKT- Hdc is a potent inhibitor of Cx43 channels with specificity for the pS368 phospho-isoform

脂化连接蛋白模拟肽 SRPTEKT-Hdc 是 Cx43 通道的强效抑制剂,对 pS368 磷酸化异构体具有特异性

Maura L Cotter, Scott Boitano, Paul D Lampe, Joell L Solan, Josef Vagner, Jose F Ek-Vitorin, Janis M Burt

Genetic Variation in Surfactant Protein-A2 Delays Resolution of Eosinophilia in Asthma

表面活性蛋白A2基因变异延缓哮喘嗜酸性粒细胞增多症的消退

Alane Blythe C Dy ,Muhammad Z Arif ,Kenneth J Addison ,Loretta G Que ,Scott Boitano ,Monica Kraft ,Julie G Ledford

Protease-activated receptor-2 signaling through β-arrestin-2 mediates Alternaria alkaline serine protease-induced airway inflammation

蛋白酶激活受体-2 信号通过 β-arrestin-2 介导链格孢碱性丝氨酸蛋白酶诱导的呼吸道炎症

Michael C Yee, Heddie L Nichols, Danny Polley, Mahmoud Saifeddine, Kasturi Pal, Kyu Lee, Emma H Wilson, Michael O Daines, Morley D Hollenberg, Scott Boitano, Kathryn A DeFea