日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Discovery of Branebrutinib (BMS-986195): A Strategy for Identifying a Highly Potent and Selective Covalent Inhibitor Providing Rapid in Vivo Inactivation of Bruton's Tyrosine Kinase (BTK)

Branebrutinib (BMS-986195) 的发现：一种识别高效且选择性共价抑制剂的策略，可快速在体内灭活布鲁顿酪氨酸激酶 (BTK)

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.9b00167
Scott H Watterson, Qingjie Liu, Myra Beaudoin Bertrand, Douglas G Batt, Ling Li, Mark A Pattoli, Stacey Skala, Lihong Cheng, Mary T Obermeier, Robin Moore, Zheng Yang, Rodney Vickery, Paul A Elzinga, Lorell Discenza, Celia D'Arienzo, Kathleen M Gillooly, Tracy L Taylor, Claudine Pulicicchio, Yifan Z
信号转导
发表日期：2019
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Bruton's tyrosine kinase inhibitor BMS-986142 in experimental models of rheumatoid arthritis enhances efficacy of agents representing clinical standard-of-care

布鲁顿酪氨酸激酶抑制剂 BMS-986142 在类风湿关节炎实验模型中增强了代表临床治疗标准的药物的疗效

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0181782
Kathleen M Gillooly, Claudine Pulicicchio, Mark A Pattoli, Lihong Cheng, Stacey Skala, Elizabeth M Heimrich, Kim W McIntyre, Tracy L Taylor, Daniel W Kukral, Shailesh Dudhgaonkar, Jignesh Nagar, Dana Banas, Scott H Watterson, Joseph A Tino, Aberra Fura, James R Burke
免疫
关节炎
发表日期：2017
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Small molecule antagonist of leukocyte function associated antigen-1 (LFA-1): structure-activity relationships leading to the identification of 6-((5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)nicotinic acid (BMS-688521)

白细胞功能相关抗原-1 (LFA-1) 的小分子拮抗剂：结构-活性关系导致鉴定 6-((5S,9R)-9-(4-氰基苯基)-3-(3,5-二氯苯基)-1-甲基-2,4-二氧代-1,3,7-三氮杂螺[4.4]壬-7-基)烟酸 (BMS-688521)

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm100348u
Scott H Watterson, Zili Xiao, Dharmpal S Dodd, David R Tortolani, Wayne Vaccaro, Dominique Potin, Michele Launay, Dawn K Stetsko, Stacey Skala, Patric M Davis, Deborah Lee, Xiaoxia Yang, Kim W McIntyre, Praveen Balimane, Karishma Patel, Zheng Yang, Punit Marathe, Pathanjali Kadiyala, Andrew J Tebben
细胞生物学
其它细胞
发表日期：2010
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